Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2020 Jul;45(7):545-546.
doi: 10.1097/RLU.0000000000003067.

Low ADC in CNS Lymphoma

Nadya Pyatigorskaya, Damien Galanaud, Didier Dormont, Carole Soussain  1 , Aurelie Kas
Affiliations
Case Reports

Low ADC in CNS Lymphoma

Nadya Pyatigorskaya et al. Clin Nucl Med. 2020 Jul.

Abstract

Patients with primary central nervous system lymphomas (PCNSLs) present with nonspecific clinical symptoms, which makes correct imaging evaluation essential for diagnostic and therapeutic management. In this work, we examined an 81-year-old man with recently discovered PCNSL using F-FDG PET/MRI, and we were able to differentiate between 2 lesions-PCNSL lymphoma extension and a recent ischemia. Our work shows that ischemia should be considered as a differential diagnosis for lymphoma progression. Although F-FDG PET or MRI alone cannot always give unambiguous solution, PET/MRI can greatly improve the diagnosis accuracy and help decide on the appropriate patient management.

PubMed Disclaimer

References

    1. Haldorsen IS, Kråkenes J, Krossnes BK, et al. CT and MR imaging features of primary central nervous system lymphoma in Norway, 1989–2003. AJNR Am J Neuroradiol. 2009;30:744–751.
    1. Phillips EH, Fox CP, Cwynarski K. Primary CNS lymphoma. Curr Hematol Malig Rep. 2014;9:243–253.
    1. Haldorsen IS, Espeland A, Larsson EM. Central nervous system lymphoma: characteristic findings on traditional and advanced imaging. AJNR Am J Neuroradiol. 2011;32:984–992.
    1. Dandois V, De Coene B, Laloux P, et al. Increased relative cerebral blood volume (rCBV) in brain lymphoma. J Neuroradiol. 2011;38:191–193.
    1. Chiavazza C, Pellerino A, Ferrio F, et al. Primary CNS lymphomas: challenges in diagnosis and monitoring. Biomed Res Int. 2018;2018:3606970.

Publication types

Substances