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Case Reports
. 2020 Aug;223(2):275-278.
doi: 10.1016/j.ajog.2020.05.023. Epub 2020 May 13.

Visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy

Gabriela N Algarroba  1 , Patricia Rekawek  1 , Sevan A Vahanian  1 , Poonam Khullar  2 , Thomas Palaia  3 , Morgan R Peltier  3 , Martin R Chavez  4 , Anthony M Vintzileos  1
Affiliations
Case Reports

Visualization of severe acute respiratory syndrome coronavirus 2 invading the human placenta using electron microscopy

Gabriela N Algarroba et al. Am J Obstet Gynecol. 2020 Aug.
No abstract available

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Figures

Figure 1
Figure 1
Placental thick section at 1 micron stained with toluidine blue showing the terminal villi containing fetal blood vessels (10×) This area was used for transmission electron microscopy. Algarroba. Visualization of SARS-CoV-2 invading the human placenta using electron microscopy. Am J Obstet Gynecol 2020.
Figure 2
Figure 2
Transmission electron microscopy of a visible single virion invading a syncytiotrophoblast (30,000×) Algarroba. Visualization of SARS-CoV-2 invading the human placenta using electron microscopy. Am J Obstet Gynecol 2020.
Figure 3
Figure 3
Transmission electron microscopy of a visible single virion invading a syncytiotrophoblast at a higher magnification (50,000×) Algarroba. Visualization of SARS-CoV-2 invading the human placenta using electron microscopy. Am J Obstet Gynecol 2020.
Figure 4
Figure 4
Transmission electron microscopy of a single virion visualized in a syncytiotrophoblast microvillus (50,000×) Algarroba. Visualization of SARS-CoV-2 invading the human placenta using electron microscopy. Am J Obstet Gynecol 2020.
Figure 5
Figure 5
Transmission electron microscopy of the trophoblastic layer in the mesenchymal core of the terminal villus where a single virion was visible, likely in the cell processes of fibroblasts (50,000×) Algarroba. Visualization of SARS-CoV-2 invading the human placenta using electron microscopy. Am J Obstet Gynecol 2020.
Figure 6
Figure 6
Transmission electron microscopy of the trophoblastic layer in the mesenchymal core of the terminal villus where 2 virions were visible, likely in the cell processes of fibroblasts (50,000×) Algarroba. Visualization of SARS-CoV-2 invading the human placenta using electron microscopy. Am J Obstet Gynecol 2020.
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References

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