Pruritis: A Vexing Problem With a Promising New Therapy

James B Wetmore^{1

2}

Affiliations

¹ Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota, USA.
² Division of Nephrology, Hennepin County Medical Center, University of Minnesota, Minneapolis, Minnesota, USA.

Editorial

James B Wetmore. Kidney Int Rep. 2020.

. 2020 Mar 18;5(5):577-579.

doi: 10.1016/j.ekir.2020.03.015. eCollection 2020 May.

James B Wetmore^{1

2}

¹ Chronic Disease Research Group, Hennepin Healthcare Research Institute, Minneapolis, Minnesota, USA.
² Division of Nephrology, Hennepin County Medical Center, University of Minnesota, Minneapolis, Minnesota, USA.

No abstract available

Comment on

Randomized Controlled Trial of Difelikefalin for Chronic Pruritus in Hemodialysis Patients.
Fishbane S, Mathur V, Germain MJ, Shirazian S, Bhaduri S, Munera C, Spencer RH, Menzaghi F; Trial Investigators. Fishbane S, et al. Kidney Int Rep. 2020 Jan 28;5(5):600-610. doi: 10.1016/j.ekir.2020.01.006. eCollection 2020 May. Kidney Int Rep. 2020. PMID: 32405581 Free PMC article.

1. Rayner H.C., Larkina M., Wang M. International comparisons of prevalence, awareness, and treatment of pruritus in people on hemodialysis. Clin J Am Soc Nephrol. 2017;12:2000–2007. - PMC - PubMed
1. Mathur V.S., Lindberg J., Germain M. A longitudinal study of uremic pruritus in hemodialysis patients. Clin J Am Soc Nephrol. 2010;5:1410–1419. - PMC - PubMed
1. Manns B., Hemmelgarn B., Lillie E. Setting research priorities for patients on or nearing dialysis. Clin J Am Soc Nephrol. 2014;9:1813–1821. - PMC - PubMed
1. Pisoni R.L., Wikstrom B., Elder S.J. Pruritus in haemodialysis patients: international results from the Dialysis Outcomes and Practice Patterns Study (DOPPS) Nephrol Dial Transplant. 2006;21:3495–3505. - PubMed
1. Narita I., Alchi B., Omori K. Etiology and prognostic significance of severe uremic pruritus in chronic hemodialysis patients. Kidney Int. 2006;69:1626–1632. - PubMed