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Case Reports
. 2020 Sep;296(3):E184-E185.
doi: 10.1148/radiol.2020201753. Epub 2020 May 14.

COVID-19-associated Leukoencephalopathy

Jeffrey R Sachs  1 , Kevin W Gibbs  1 , Dionne E Swor  1 , Adam P Sweeney  1 , Daniel W Williams  1 , Jonathan H Burdette  1 , Thomas G West  1 , Carol P Geer  1
Affiliations
Case Reports

COVID-19-associated Leukoencephalopathy

Jeffrey R Sachs et al. Radiology. 2020 Sep.
No abstract available

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Figures

Unenhanced CT image of head demonstrates confluent hypoattenuation in genu (anterior) and splenium (posterior) of corpus callosum (arrows).
Figure 1:
Unenhanced CT image of head demonstrates confluent hypoattenuation in genu (anterior) and splenium (posterior) of corpus callosum (arrows).
(a) T2-weighted fluid-attenuated inversion recovery MRI scan of brain shows extensive posterior greater than anterior white matter hyperintensity (arrows) without mass effect. (b) Susceptibility-weighted image demonstrates a cluster of microhemorrhages in corpus callosum (arrows). (c) Arterial-spin-labeling perfusion images are suggestive of posterior circulation hyperperfusion (arrows). CBF = cerebral blood flow.
Figure 2a:
(a) T2-weighted fluid-attenuated inversion recovery MRI scan of brain shows extensive posterior greater than anterior white matter hyperintensity (arrows) without mass effect. (b) Susceptibility-weighted image demonstrates a cluster of microhemorrhages in corpus callosum (arrows). (c) Arterial-spin-labeling perfusion images are suggestive of posterior circulation hyperperfusion (arrows). CBF = cerebral blood flow.
(a) T2-weighted fluid-attenuated inversion recovery MRI scan of brain shows extensive posterior greater than anterior white matter hyperintensity (arrows) without mass effect. (b) Susceptibility-weighted image demonstrates a cluster of microhemorrhages in corpus callosum (arrows). (c) Arterial-spin-labeling perfusion images are suggestive of posterior circulation hyperperfusion (arrows). CBF = cerebral blood flow.
Figure 2b:
(a) T2-weighted fluid-attenuated inversion recovery MRI scan of brain shows extensive posterior greater than anterior white matter hyperintensity (arrows) without mass effect. (b) Susceptibility-weighted image demonstrates a cluster of microhemorrhages in corpus callosum (arrows). (c) Arterial-spin-labeling perfusion images are suggestive of posterior circulation hyperperfusion (arrows). CBF = cerebral blood flow.
(a) T2-weighted fluid-attenuated inversion recovery MRI scan of brain shows extensive posterior greater than anterior white matter hyperintensity (arrows) without mass effect. (b) Susceptibility-weighted image demonstrates a cluster of microhemorrhages in corpus callosum (arrows). (c) Arterial-spin-labeling perfusion images are suggestive of posterior circulation hyperperfusion (arrows). CBF = cerebral blood flow.
Figure 2c:
(a) T2-weighted fluid-attenuated inversion recovery MRI scan of brain shows extensive posterior greater than anterior white matter hyperintensity (arrows) without mass effect. (b) Susceptibility-weighted image demonstrates a cluster of microhemorrhages in corpus callosum (arrows). (c) Arterial-spin-labeling perfusion images are suggestive of posterior circulation hyperperfusion (arrows). CBF = cerebral blood flow.
See this image and copyright information in PMC

References

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    1. Pinto PS, Taipa R, Moreira B, Correia C, Melo-Pires M. Acute hemorrhagic leukoencephalitis with severe brainstem and spinal cord involvement: MRI features with neuropathological confirmation. J Magn Reson Imaging 2011;33(4):957–961. - PubMed
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