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. 2020 May;7(3):033501.
doi: 10.1117/1.JMI.7.3.033501. Epub 2020 May 12.

Evaluation of a hybrid direct-indirect active matrix flat-panel imager using Monte Carlo simulation

Affiliations

Evaluation of a hybrid direct-indirect active matrix flat-panel imager using Monte Carlo simulation

Scott Dow et al. J Med Imaging (Bellingham). 2020 May.

Abstract

Purpose: Monte Carlo simulations were used to evaluate the imaging properties of a composite direct-indirect active matrix flat-panel imager (AMFPI) with potentially more favorable tradeoffs between x-ray quantum efficiency and spatial resolution than direct or indirect AMFPIs alone. This configuration, referred to as a hybrid AMFPI, comprises a scintillator that is optically coupled to an a-Se direct AMFPI through a transparent electrode and hole blocking layer, such that a-Se acts as both a direct x-ray converter and an optical sensor. Approach: GEANT4 was used to simulate x-ray energy deposition, optical transport, and charge signal generation processes in various hybrid AMPFI configurations under RQA5 and RQA9 x-ray beam conditions. The Fujita-Lubberts-Swank method was used to quantify the impact of irradiation geometry, x-ray converter thicknesses, conversion gain of each layer, and x-ray cross talk between layers on detective quantum efficiency (DQE). Results: Each hybrid configuration had a greater DQE than its direct AMFPI layer alone. The DQE improvement was largest at low spatial frequencies in both front- and back-irradiation (BI) geometries due to increased x-ray quantum efficiency provided by the scintillator. DQE improvements persisted at higher frequencies in BI geometry due to preferential x-ray absorption in a-Se. Matching the x-ray-to-charge conversion gains of a hybrid AMFPI's direct and indirect detection layers affects its Swank factor and, thus, DQE(0). X-ray cross talk has a negligible impact on the DQE ( f ) of hybrid AMFPIs with sufficiently high optical quantum efficiency. Conclusion: An optimized hybrid AMFPI can achieve greater DQE performance than current direct or indirect AMFPIs.

Keywords: active matrix flat-panel imager; amorphous selenium; detective quantum efficiency; digital radiography; flat-panel detector; scintillator.

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Figures

Fig. 1
Fig. 1
(a) Schematic of a direct AMFPI. X-rays are converted directly into charge via the photoconductor, which is read out by the TFT array. (b) Schematic of an indirect AMFPI. X-rays are converted into optical photons, which are then converted into charge and read out by a photodiode-TFT array. BI of indirect AMFPIs results in greater light escape efficiency and less blur and image noise than FI.
Fig. 2
Fig. 2
Schematic of a hybrid AMFPI. Both a-Se and the scintillator function as x-ray converters. X-rays absorbed in a-Se are converted directly into charge. X-rays absorbed in the scintillator are converted into optical photons, which are detected at the scintillator/a-Se interface and converted into charge. Charge is then read out by the TFT array.
Fig. 3
Fig. 3
(a) Schematic of our hybrid AMFPI model, which consists of GOS, a-Se, and TFT substrate glass. Four types of x-ray interactions are possible. Type 1 interactions only deposit energy in a-Se and only result in a direct signal component. Type 2 interactions only deposit energy in GOS and only result in an indirect signal component. Type 3 and 4 interactions result in x-ray cross talk from a-Se into GOS and GOS into a-Se, respectively, which occur due to either x-ray scatter or fluorescence. (b) Relative intensity plots of RQA5 and RQA9 x-ray spectra, which have average energies of 52 and 76 keV, respectively.
Fig. 4
Fig. 4
A schematic depicting the methods used to calculate various detector performance metrics. Row 1: By integrating each single x-ray response, S(r), in 2D, the total signal magnitude due to each x-ray, S, is derived. Each measurement of S is then binned in a histogram to determine the PHS, which is used to calculate the Swank factor AS and DQE(0). Row 2: The S(r) ensemble is spaced uniformly along an infinitely thin slanted slit, from which MTF(f) is computed via Fujita’s method. Row 3: Each S(r) is integrated along the y-axis to derive S(x). Fourier analysis is performed to compute qNNPS(f). DQE(f) is then found from MTF(f) and qNNPS(f).
Fig. 5
Fig. 5
DQE(f) of a hybrid AMFPI in FI and BI geometries for both (a) RQA5 and (b) RQA9 beam qualities. Both a-Se and GOS thicknesses were 300  μm, and optimal gain matching was assumed using β=0.44 and WSe=50  eV. BI results in a significant increase in DQE(f) at higher frequencies compared to FI.
Fig. 6
Fig. 6
DQE(f) of hybrid AMFPIs with a GOS thickness of 300  μm and various a-Se thicknesses at (a) RQA5 and (b) RQA9. Optimal gain matching was assumed using β=0.44 and WSe=50  eV. Greater a-Se thickness increases DQE(f) at all frequencies, particularly when using lower energy x-ray spectra such as RQA5.
Fig. 7
Fig. 7
DQE(f) of hybrid AMFPIs with an a-Se thickness of 300  μm and various GOS thicknesses at (a) RQA5 and (b) RQA9. Optimal gain matching was assumed using β=0.44 and WSe=50  eV. Greater GOS thickness increases DQE(f) at lower frequencies, particularly when using higher energy x-ray spectra such as RQA9.
Fig. 8
Fig. 8
PHSGOS (blue) and PHSa-Se (magenta) using different values of β and WSe. Greater overlap increases DQE(0). Dashed lines indicate averages. (a) β=1, WSe=50  eV; (b) β=0.44, WSe=50  eV; and (c) β=1, WSe=22  eV.
Fig. 9
Fig. 9
(a) Hybrid AMFPI DQE(0) (dark blue) as a function of β, with WSe=50  eV. (b) Hybrid AMFPI DQE(0) (magenta) as a function of WSe with β=1. DQE(0) of a-Se alone with WSe=50  eV is shown in teal in both plots.
Fig. 10
Fig. 10
(a) A contour plot of DQE(0) as a function of β and WSe. Warmer colors indicate higher values. DQE(0) reaches a maximum of 0.678 (dark red) whenever optimal gain matching is achieved. Black curves trace paths through β and WSe as a function of ESe for various values of λ. 5  Vμm1 intervals are marked by asterisks. (b) DQE(0) versus ESe for various values of λ. When ESe is larger than 5  Vμm1, DQE(0) is primarily a function of λ.
Fig. 11
Fig. 11
(a) The x-ray induced luminescence spectrum of GOS and the spectral sensitivity of a-Se both with and without Te doping. (b) DQE(f) of a-Se alone (blue) and the hybrid AMFPI using GOS both with (red) and without (teal) Te doped a-Se.
Fig. 12
Fig. 12
(a) PHS consisting of only the indirect component of signal. Counts due to GOS x-ray interactions are shown in blue, while those due to a-Se cross talk are shown in green. Cross talk results in an additional peak at 280  ehp due to a-Se K-fluorescence, which is negligible in magnitude. (b) PHS consisting of only the direct component of signal. Cross talk results in two additional peaks contained within that of a-Se due to gadolinium K-fluorescence. Counts due to a-Se x-ray interactions are shown in blue, while those due to GOS cross talk are shown in green. (c) Hybrid AMFPI DQE(f) of both direct and indirect signal components is shown with and without cross talk. Only cross talk from GOS into Se was significant, resulting in an increase at low f with a degradation at all other f.

References

    1. Rowlands J. A., Yorkston J., “Flat panel detectors for digital radiography,” in Handbook of Medical Imaging, Van Metter R. L., Beutel J., Kundel H. L., Eds., Vol. 1, pp. 223–328, SPIE Press, Bellingham, Washington: (2000).
    1. Kabir M. Z., Kasap S., “Photoconductors for x-ray image detectors,” in Springer Handbook of Electronic and Photonic Materials, Kasap S., Capper P., Eds., pp. 1–1, Springer, Cham: (2017).
    1. Jiang H., et al. , “Development of active matrix flat panel imagers incorporating thin layers of polycrystalline HgI2 for mammographic x-ray imaging,” Phys. Med. Biol. 58(3), 703 (2013).PHMBA710.1088/0031-9155/58/3/703 - DOI - PMC - PubMed
    1. Semeniuk O., et al. , “Characterization of polycrystalline lead oxide for application in direct conversion x-ray detectors,” Sci. Rep. 7(1), 8659 (2017).SRCEC310.1038/s41598-017-09168-3 - DOI - PMC - PubMed
    1. Yakunin S., et al. , “Detection of x-ray photons by solution-processed lead halide perovskites,” Nat. Photonics 9(7), 444 (2015).NPAHBY10.1038/nphoton.2015.82 - DOI - PMC - PubMed