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. 2020 Jul;16(20):1455-1461.
doi: 10.2217/fon-2020-0361. Epub 2020 May 15.

The management of patients with metastatic prostate cancer during the COVID-19 pandemic

Tarek Assi  1 , Nathalie Ibrahim  1 , Rita-Maria K Abboud  1 , Clarisse Kattan  1 , Elie Rassy  1 , Elie Nemr  2 , Joseph Kattan  1
Affiliations

The management of patients with metastatic prostate cancer during the COVID-19 pandemic

Tarek Assi et al. Future Oncol. 2020 Jul.

Abstract

During the ongoing global pandemic of coronavirus disease 2019 (COVID-19), the benefit of treating patients with cancer must be weighed against the COVID-19 infection risks to patients, staff and society. Prostate cancer is one of the most common cancers among men and raises particular interest during the pandemic as recent reports show that the TMPRSS2 (and other serine proteases), which facilitate the entry, replication and budding of the virion from a cell, can be inhibited using androgen deprivation therapy. Nevertheless, patients with metastatic prostate cancer commonly receive chemotherapy which may compromise their immune system. This paper aims to address the current status of the COVID-19 in patients with cancer overall and suggests an optimal approach to patients with metastatic prostate cancer.

Keywords: COVID-19; castrate resistant; coronavirus; hormone sensitive; immunosuppression; metastatic; prostate cancer.

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Conflict of interest statement

Financial & competing interests disclosure

The authors have no relevant affiliations or financial involvement with any organization or entity with a financial interest in or financial conflict with the subject matter or materials discussed in the manuscript. This includes employment, consultancies, honoraria, stock ownership or options, expert testimony, grants or patents received or pending, or royalties.

No writing assistance was utilized in the production of this manuscript.

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