Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 May;7(1):e000408.
doi: 10.1136/bmjgast-2020-000408.

Endoscopic ultrasound (EUS) and the management of pancreatic cancer

Affiliations
Review

Endoscopic ultrasound (EUS) and the management of pancreatic cancer

Muhammad Nadeem Yousaf et al. BMJ Open Gastroenterol. 2020 May.

Abstract

Pancreatic cancer is one of the leading causes of cancer-related mortality in western countries. Early diagnosis of pancreatic cancers plays a key role in the management by identification of patients who are surgical candidates. The advancement in the radiological imaging and interventional endoscopy (including endoscopic ultrasound (EUS), endoscopic retrograde cholangiopancreatography and endoscopic enteral stenting techniques) has a significant impact in the diagnostic evaluation, staging and treatment of pancreatic cancer. The multidisciplinary involvement of radiology, gastroenterology, medical oncology and surgical oncology is central to the management of patients with pancreatic cancers. This review aims to highlight the diagnostic and therapeutic role of EUS in the management of patients with pancreatic malignancy, especially pancreatic ductal adenocarcinoma.

Keywords: endoscopic procedures; endoscopic ultrasonography; pancreatic cancer; pancreatic disorders; pancreato-biliary disorders.

PubMed Disclaimer

Conflict of interest statement

Competing interests: None declared.

Figures

Figure 1
Figure 1
Algorithm for the evaluation and management of patients with suspected pancreatic adenocarcinoma (courtesy of American society of gastrointestinal endoscopy (ASGE) practice guidelines). EUS, endoscopic ultrasound; ERCP, endoscopic retrograde cholangiopancreatography; FNA, fine-needle aspiration.

References

    1. Siegel RL, Miller KD, Jemal A. Cancer statistics, 2018. CA Cancer J Clin 2018;68:7–30. 10.3322/caac.21442 - DOI - PubMed
    1. Ilic M, Ilic I. Epidemiology of pancreatic cancer. World J Gastroenterol 2016;22:9694–705. 10.3748/wjg.v22.i44.9694 - DOI - PMC - PubMed
    1. Parkin DM, Boyd L, Walker LC. 16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010. Br J Cancer 2011;105 Suppl 2:S77–81. 10.1038/bjc.2011.489 - DOI - PMC - PubMed
    1. Willett WC. Diet and cancer. Oncologist 2000;5:393–404. 10.1634/theoncologist.5-5-393 - DOI - PubMed
    1. Bosetti C, Bertuccio P, Negri E, et al. . Pancreatic cancer: overview of descriptive epidemiology. Mol Carcinog 2012;51:3–13. 10.1002/mc.20785 - DOI - PubMed

MeSH terms