Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Sep:142:109828.
doi: 10.1016/j.mehy.2020.109828. Epub 2020 May 11.

As a potential treatment of COVID-19: Montelukast

Cihan Fidan  1 , Ayşe Aydoğdu  2
Affiliations

As a potential treatment of COVID-19: Montelukast

Cihan Fidan et al. Med Hypotheses. 2020 Sep.

Abstract

It has been hypothesized that Montelukast, a cysteinyl leukotriene (cysLT) receptor antagonist, with effects of anti-inflammatory, suppress oxidative stress and reduce affect cytokine production, may limited progression of the disease on COVID-19 infection.

PubMed Disclaimer

Conflict of interest statement

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

References

    1. Rodriguez-Morales A.J., Cardona-Ospina J.A., Gutierrez-Ocampo E., Villamizar-Pena R., Holguin-Rivera Y., Escalera-Antezana J.P. Clinical, laboratory and imaging features of COVID-19: A systematic review and meta-analysis. Travel Med Infect Dis. 2020:101623. PubMed PMID: 32179124. Epub 2020/03/18. eng. - PMC - PubMed
    1. Zhang J.J., Dong X., Cao Y.Y., Yuan Y.D., Yang Y.B., Yan Y.Q. Clinical characteristics of 140 patients infected with SARS-CoV-2 in Wuhan, China. Allergy. 2020 PubMed PMID: 32077115. Epub 2020/02/23. eng. - PubMed
    1. Chen X, Zhang X, Pan J. Effect of Montelukast on Bronchopulmonary Dysplasia (BPD) and Related Mechanisms. Medical science monitor : int Med J Exp Clin Res 2019 Mar 13; 25: 1886-93. PubMed PMID: 30862773. Pubmed Central PMCID: PMC6427930. Epub 2019/03/14. eng. - PMC - PubMed
    1. Sarzi-Puttini P., Giorgi V., Sirotti S., Marotto D., Ardizzone S., Rizzardini G. COVID-19, cytokines and immunosuppression: what can we learn from severe acute respiratory syndrome? Clin Exp Rheumatol. 2020;38(2):337–342. PubMed PMID: 32202240. Epub 2020/03/2eng. - PubMed
    1. Bisgaard H., Flores-Nunez A., Goh A., Azimi P., Halkas A., Malice M.P. Study of montelukast for the treatment of respiratory symptoms of post-respiratory syncytial virus bronchiolitis in children. Am J Respir Critical Care Med. 2008;178(8):854–860. PubMed PMID: 18583576. Epub 2008/06/28. eng. - PubMed