COVID-19 in a patient with severe chronic rhinosinusitis with nasal polyps during therapy with dupilumab

Affiliations

¹ Department of Otorhinolaryngology, Head and Neck Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt- Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
² Upper Airways Research Laboratory and Department of Oto-Rhino-Laryngology, Ghent University, Ghent, Belgium, Germany.
³ Department of Otorhinolaryngology, Head and Neck Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt- Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Electronic address: heidi.olze@charite.de.

Case Reports

Ulrike Förster-Ruhrmann et al. J Allergy Clin Immunol. 2020 Jul.

. 2020 Jul;146(1):218-220.e2.

doi: 10.1016/j.jaci.2020.05.005. Epub 2020 May 15.

¹ Department of Otorhinolaryngology, Head and Neck Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt- Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.
² Upper Airways Research Laboratory and Department of Oto-Rhino-Laryngology, Ghent University, Ghent, Belgium, Germany.
³ Department of Otorhinolaryngology, Head and Neck Surgery, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt- Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany. Electronic address: heidi.olze@charite.de.

No abstract available

References

1. Bachert C., Han J.K., Desrosiers M., Hellings P.W., Amin N., Lee S.E. Efficacy and safety of dupilumab in patients with severe chronic rhinosinusitis with nasal polyps (LIBERTY NP SINUS-24 and LIBERTY NP SINUS-52): results from two multicentre, randomised, double-blind, placebo-controlled, parallel-group phase 3 trials. Lancet. 2019;394:1638–1650. - PubMed
1. Nathan R.A., Sorkness C.A., Kosinski M., Schatz M., Li J.T., Marcus P. Development of the asthma control test: a survey for assessing asthma control. J Allergy Clin Immunol. 2004;113:59–65. - PubMed
1. Hopkins C., Gillett S., Slack R., Lund V.J., Browne J.P. Psychometric validity of the 22-item Sinonasal Outcome Test. Clin Otolaryngol. 2009;34:447–454. - PubMed
1. Liu F., Xu A., Zhang Y., Xuan W., Yan T., Pan K. Patients of COVID-19 may benefit from sustained lopinavir-combined regimen and the increase of eosinophil may predict the outcome of COVID-19 progression. Int J Infect Dis. 2020;95:183–191. - PMC - PubMed
1. Wollenberg A., Beck L.A., Blauvelt A., Simpson E.L., Chen Z., Chen Q. Laboratory safety of dupilumab in moderate-to-severe atopic dermatitis: results from three phase III trials (LIBERTY AD SOLO 1, LIBERTY AD SOLO 2, LIBERTY AD CHRONOS) Br J Dermatol. 2020;182:1120–1135. - PMC - PubMed