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Editorial
. 2020 Apr;9(2):180-183.
doi: 10.21037/tlcr.2020.03.07.

From precision medicine to imprecision medicine through limited diagnostic ability to detect low allelic frequency mutations

María José Serrano  1   2   3 , José Exposito-Hernández  2 , Rosa Guerrero  2 , Javier Lopez-Hidalgo  4 , Mariano Aguilar  3 , Jose A Lorente  1   5 , Enrique de Álava  6   7 , M Carmen Garrido-Navas  1
Affiliations
Editorial

From precision medicine to imprecision medicine through limited diagnostic ability to detect low allelic frequency mutations

María José Serrano et al. Transl Lung Cancer Res. 2020 Apr.
No abstract available

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Conflict of interest statement

Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at http://dx.doi.org/10.21037/tlcr.2020.03.07). The authors have no conflicts of interest to declare.

Figures

Figure 1
Figure 1
Sensitivity assessment of matrix-assisted laser time-of-flight desorption/ionization (MALDI-TOF), allele-specific polymerase chain reaction (AS-PCR) and droplet digital PCR (ddPCR) detecting low allelic frequencies in epithelial growth factor receptor (EGFR) gene and their influence selecting a more precise treatment. Abbreviations are: TKI, tyrosine kinase inhibitors; mAF, mutated allele frequency.
See this image and copyright information in PMC

Comment on

References

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