Patients with sickle cell disease and suspected COVID-19 in a paediatric intensive care unit

Affiliations

¹ Réanimation et Soins Continus Medico-chirurgicaux, Hôpital Necker-Enfants Malades, APHP Paris, Paris, France.
² Service d'imagerie médicale pédiatrique, Hôpital Necker Enfants Malades, APHP Paris, Paris, France.
³ Unité d'hémaphérèse thérapeutique, Hôpital Necker-Enfants Malades, APHP Paris, Paris, France.
⁴ Pédiatrie générale, Centre de la drépanocytose, Hôpital Armand Trousseau, APHP, Université Paris, Paris, Sorbonne, France.
⁵ Laboratoire de Virologie, Hôpital Necker-Enfants Malades, Paris University, APHP Paris, Paris, France.
⁶ Pédiatrie générale et maladies infectieuses, Centre de référence de la drépanocytose, Hôpital Necker-Enfants Malades, APHP Paris, Paris, France.

Observational Study

Claire Heilbronner et al. Br J Haematol. 2020 Jul.

. 2020 Jul;190(1):e21-e24.

doi: 10.1111/bjh.16802. Epub 2020 Jun 8.

¹ Réanimation et Soins Continus Medico-chirurgicaux, Hôpital Necker-Enfants Malades, APHP Paris, Paris, France.
² Service d'imagerie médicale pédiatrique, Hôpital Necker Enfants Malades, APHP Paris, Paris, France.
³ Unité d'hémaphérèse thérapeutique, Hôpital Necker-Enfants Malades, APHP Paris, Paris, France.
⁴ Pédiatrie générale, Centre de la drépanocytose, Hôpital Armand Trousseau, APHP, Université Paris, Paris, Sorbonne, France.
⁵ Laboratoire de Virologie, Hôpital Necker-Enfants Malades, Paris University, APHP Paris, Paris, France.
⁶ Pédiatrie générale et maladies infectieuses, Centre de référence de la drépanocytose, Hôpital Necker-Enfants Malades, APHP Paris, Paris, France.

No abstract available

Keywords: COVID-19; acute chest syndrome; children; intensive care; sickle cell disease.

Figures

A pediatric patient with sickle cell disease presenting with severe anemia and splenic sequestration in the setting of COVID-19.
Jacob S, Dworkin A, Romanos-Sirakis E. Jacob S, et al. Pediatr Blood Cancer. 2020 Dec;67(12):e28511. doi: 10.1002/pbc.28511. Epub 2020 Aug 9. Pediatr Blood Cancer. 2020. PMID: 32776396 Free PMC article. No abstract available.

1. Hussain FA, Njoku FU, Saraf SL, Molokie RE, Gordeuk VR, Han J. COVID‐19 infection in patients with sickle cell disease. Br J Haematol. 2020. [Epub ahead of print]. DOI: 10.1111/bjh.16734. - DOI - PMC - PubMed
1. De Luna G, Habibi A, Deux JF, Colard M, d'Alexandry d'Orengiani AL, Schlemmer F, et al. Rapid and severe Covid‐19 pneumonia with severe acute chest syndrome in a sickle cell patient successfully treated with tocilizumab. Am J Hematol. 2020. [Epub ahead of print]. DOI: 10.1002/ajh.25833. - DOI - PMC - PubMed
1. Nur E, Gaartman AE, van Tuijn CFJ, Tang MW, Biemond BJ. Vaso‐occlusive crisis and acute chest syndrome in sickle cell disease due to 2019 novel coronavirus disease (COVID‐19). Am J Hematol. 2020;95:725–6. - PMC - PubMed
1. Beerkens F, John M, Puliafito B, Corbett V, Edwards C, Tremblay D. COVID‐19 pneumonia as a cause of acute chest syndrome in an adult sickle cell patient. Am J Hematol. 2020. [Epub ahead of print]. DOI: 10.1002/ajh.25809. - DOI - PubMed
1. Vichinsky EP, Styles LA, Colangelo LH, Wright EC, Castro O, Nickerson B. Acute chest syndrome in sickle cell disease: clinical presentation and course. Cooperative Study of Sickle Cell Disease. Blood. 1997;89:1787–92. - PubMed