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Meta-Analysis
. 2020 Jul;30(4):e2113.
doi: 10.1002/rmv.2113. Epub 2020 May 18.

Three months of COVID-19: A systematic review and meta-analysis

Affiliations
Meta-Analysis

Three months of COVID-19: A systematic review and meta-analysis

Danish Rafiq et al. Rev Med Virol. 2020 Jul.

Abstract

The pandemic of 2019 novel coronavirus (SARS-CoV-2019), reminiscent of the 2002-SARS-CoV outbreak, has completely isolated countries, disrupted health systems and partially paralyzed international trade and travel. In order to be better equipped to anticipate transmission of this virus to new regions, it is imperative to track the progress of the virus over time. This review analyses information on progression of the pandemic in the past 3 months and systematically discusses the characteristics of SARS-CoV-2019 virus including its epidemiologic, pathophysiologic, and clinical manifestations. Furthermore, the review also encompasses some recently proposed conceptual models that estimate the spread of this disease based on the basic reproductive number for better prevention and control procedures. Finally, we shed light on how the virus has endangered the global economy, impacting it both from the supply and demand side.

Keywords: ACE-2; COVID-19; SARS-CoV; mathematical modeling; pandemic.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
A timeline of COVID‐19
FIGURE 2
FIGURE 2
Genome organization and life‐cycle of SARS‐nCoV‐2
FIGURE 3
FIGURE 3
A conceptual SEIR model for COVID‐19
FIGURE 4
FIGURE 4
Timeline of R 0 for COVID‐19

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