Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
- PMID: 32422375
- PMCID: PMC7211669
- DOI: 10.1016/j.ijid.2020.05.025
Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19
Abstract
The current global propagation of COVID-19 is heterogeneous, with slow transmission continuing in many countries and exponential propagation in others, where the time that it took for the explosive spread to begin varied greatly. It is proposed that this could be explained by cascading superspreading events, in which new infections caused by a superspreader are more likely to be highly infectious. The mechanism suggested for this is related to viral loads. Exposure to high viral loads may result in high-intensity infection, which exposes new cases to high viral loads. This notion is supported by experimental veterinary research.
Keywords: COVID-19; Epidemiology; Propagation; SARS-CoV-2; Superspreader; Superspreading; Transmission.
Copyright © 2020 The Author. Published by Elsevier Ltd.. All rights reserved.
Comment in
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The prominence of asymptomatic superspreaders in transmission mean universal face masking should be part of COVID-19 de-escalation strategies.Int J Infect Dis. 2020 Aug;97:21-22. doi: 10.1016/j.ijid.2020.05.102. Epub 2020 Jun 1. Int J Infect Dis. 2020. PMID: 32497799 Free PMC article. No abstract available.
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Superspreaders and the spread pattern of COVID-19: Response to: 'Do superspreaders generate new superspreaders? A hypothesis to explain the propagation pattern of COVID-19'. Int J Infect Dis 2020;96:461-3.Int J Infect Dis. 2020 Sep;98:381. doi: 10.1016/j.ijid.2020.06.102. Epub 2020 Jul 2. Int J Infect Dis. 2020. PMID: 32623084 Free PMC article. No abstract available.
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Response to Gal Almogy: Superspreaders do matter.Int J Infect Dis. 2020 Sep;98:187. doi: 10.1016/j.ijid.2020.06.100. Epub 2020 Jul 2. Int J Infect Dis. 2020. PMID: 32623085 Free PMC article. No abstract available.
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