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Case Reports
. 2020 Aug;21(8):946-949.
doi: 10.1016/j.carrev.2020.05.009. Epub 2020 May 15.

COVID-19 (SARS-CoV-2) and the Heart - An Ominous Association

Nauman Khalid  1 , Yuefeng Chen  1 , Brian C Case  1 , Evan Shlofmitz  1 , Jason P Wermers  1 , Toby Rogers  2 , Itsik Ben-Dor  1 , Ron Waksman  3
Affiliations
Case Reports

COVID-19 (SARS-CoV-2) and the Heart - An Ominous Association

Nauman Khalid et al. Cardiovasc Revasc Med. 2020 Aug.

Abstract

Coronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Cardiovascular manifestations of COVID-19 are diverse and complex and include acute coronary syndrome, myocarditis masquerading as ST-segment elevation myocardial infarction, pericarditis and pericardial effusion. We present 2 cases of COVID-19 infection with myocardial involvement with distinct mechanistic pathways and outcomes. Important decision strategies such as the timing of cardiac catheterization (when indicated) and requirement of early hemodynamic support in critically ill patients are discussed.

Keywords: Acute coronary syndrome; COVID-19; Complications; Myocarditis; Severe acute respiratory syndrome coronavirus 2.

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Conflict of interest statement

Toby Rogers – Consultant and proctor: Medtronic, Edwards Lifesciences; Advisory board: Medtronic. Equity interest: Transmural Systems. Ron Waksman – Advisory Board: Amgen, Boston Scientific, Cardioset, Cardiovascular Systems Inc., Medtronic, Philips, Pi-Cardia Ltd.; Consultant: Amgen, Biotronik, Boston Scientific, Cardioset, Cardiovascular Systems Inc., Medtronic, Philips, Pi-Cardia Ltd.; Grant Support: AstraZeneca, Biotronik, Boston Scientific, Chiesi; Speakers Bureau: AstraZeneca, Chiesi; Investor: MedAlliance. All other authors – None.

Figures

Fig. 1
Fig. 1
12‑Lead electrocardiogram (ECG), case 1.
Fig. 2
Fig. 2
(Panels A, B, and C): Coronary angiography. CIRC = Circumflex, LAD = Left anterior descending, LMCA = Left main coronary artery, RCA = Right coronary artery, RPDA = Right posterior descending, RPLB = Right posterolateral branch.
Fig. 3
Fig. 3
ECG, case 2.
Fig. 4
Fig. 4
Sonosite point-of-care echocardiogram demonstrating a large anterior pericardial effusion (yellow star) with end-diastolic compression of the right ventricle.
See this image and copyright information in PMC

References

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