Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Jul;46(7):1494-1495.
doi: 10.1007/s00134-020-06083-6. Epub 2020 May 18.

Stages or phenotypes? A critical look at COVID-19 pathophysiology

Amit Jain  1 , D John Doyle  2
Affiliations
Comment

Stages or phenotypes? A critical look at COVID-19 pathophysiology

Amit Jain et al. Intensive Care Med. 2020 Jul.
No abstract available

PubMed Disclaimer

Conflict of interest statement

The authors declare no competing interests.

Comment in

  • From phenotypes to black holes… and back.
    Camporota L, Chiumello D, Busana M, Romitti F, Gattinoni L. Camporota L, et al. Intensive Care Med. 2020 Jul;46(7):1498-1499. doi: 10.1007/s00134-020-06124-0. Epub 2020 Jun 5. Intensive Care Med. 2020. PMID: 32504101 Free PMC article. No abstract available.

Comment on

References

    1. Gattinoni L, Chiumello D, Caironi P, et al. COVID-19 pneumonia: different respiratory treatments for different phenotypes? Intensive Care Med. 2020 doi: 10.1007/s00134-020-06033-2. - DOI - PMC - PubMed
    1. Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA. 2020 doi: 10.1001/jama.2020.1585. - DOI - PMC - PubMed
    1. Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, Zhao X, Huang B, Shi W, Lu R, Niu P, Zhan F, Ma X, Wang D, Xu W, Wu G, Gao GF, Tan W, China Novel Coronavirus I, Research T A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733. doi: 10.1056/NEJMoa2001017. - DOI - PMC - PubMed
    1. Guignabert C, de Man F, Lombès M. ACE2 as therapy for pulmonary arterial hypertension: the good outweighs the bad. Eur Respir J. 2018 doi: 10.1183/13993003.00848-2018. - DOI - PubMed
    1. Millar FR, Summers C, Griffiths MJ, Toshner MR, Proudfoot AG. The pulmonary endothelium in acute respiratory distress syndrome: insights and therapeutic opportunities. Thorax. 2006;71:462–473. doi: 10.1136/thoraxjnl-2015-207461. - DOI - PubMed

LinkOut - more resources