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Case Reports
. 1988 Mar-Apr;4(2):124-5.
doi: 10.1016/0887-8994(88)90055-0.

Magnetic resonance imaging in Pelizaeus-Merzbacher disease

C Shimomura  1 , A Matsui, H Choh, M Funahashi, Y Suzuki, K Tsuchiya
Affiliations
Case Reports

Magnetic resonance imaging in Pelizaeus-Merzbacher disease

C Shimomura et al. Pediatr Neurol. 1988 Mar-Apr.

Abstract

Cranial computed tomography of a boy with clinical characteristics of the classic form of Pelizaeus-Merzbacher disease did not reveal a notable abnormality other than enlarged ventricles. Magnetic resonance imaging, however, demonstrated diffuse changes in the white matter with sparing of scattered small areas, suggesting persistent myelin islands which are a typical neuropathologic finding in Pelizaeus-Merzbacher disease. Magnetic resonance imaging appears more useful than computed tomography in confirming the diagnosis of Pelizaeus-Merzbacher disease.

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