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Review
. 2020 Aug 1:128:147-150.
doi: 10.1016/j.amjcard.2020.04.054. Epub 2020 May 16.

Cardiovascular Safety of Potential Drugs for the Treatment of Coronavirus Disease 2019

Gaurav Aggarwal  1 , Brandon Michael Henry  2 , Saurabh Aggarwal  3 , Sripal Bangalore  4
Affiliations
Review

Cardiovascular Safety of Potential Drugs for the Treatment of Coronavirus Disease 2019

Gaurav Aggarwal et al. Am J Cardiol. .

Abstract

Coronavirus disease 2019 (COVID-19) has become a global pandemic. It is still uncontrolled in most countries and no therapies are currently available. Various drugs are under investigation for its treatment. The disease is known to have worse outcomes in patients who have underlying cardiovascular disease. Chloroquine/hydroxychloroquine, azithromycin, remdesivir and lopinavir/ritonavir are currently being studied in trials and show some promise. Conduction disorders, heart failure, and mortality have been reported with the use of these drugs. It is important to have knowledge of potential cardiotoxic effects of these drugs before using them for COVID-19 patients for better allocation of healthcare resources and improvement in clinical outcomes.

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Conflict of interest statement

Disclosures The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Comment in

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