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. 2020 Aug;46(8):2057-2069.
doi: 10.1016/j.ultrasmedbio.2020.03.011. Epub 2020 May 16.

Cardiac Tissue-Mimicking Ballistic Gel Phantom for Ultrasound Imaging in Clinical and Research Applications

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Cardiac Tissue-Mimicking Ballistic Gel Phantom for Ultrasound Imaging in Clinical and Research Applications

Natasha Alves et al. Ultrasound Med Biol. 2020 Aug.

Abstract

Ballistic gel was investigated as a tissue-mimicking material in an anthropomorphic cardiac phantom for ultrasound imaging. The gel was tested for its acoustic properties and its compatibility with conventional plastics molding techniques. Speed of sound and attenuation were evaluated in the range 2-12 MHz. The speed of sound was 1537 ± 39 m/s, close to typical values for cardiac tissue (∼1576 m/s). The attenuation coefficient was 1.07 dB/cm·MHz, within the range of values previously reported for cardiac tissue (0.81-1.81 dB/cm·MHz). A cardiac model based on human anatomy was developed using established image segmentation processes and conventional plastic molding techniques. Key anatomic features were observed, captured and identified in the model using an intracardiac ultrasound imaging system. These favorable results along with the material's durability and processes that allow for repetitive production of detailed whole-heart models at low cost are promising. There are numerous applications for geometrically complex phantoms in research, training, device development and clinical use.

Keywords: Acoustic properties; Ballistic gel; Cardiac model; Computed tomography-derived models; Heart phantom; Intracardiac echocardiography; Rapid prototyping; Tissue-mimicking materials; Transesophageal echo; Transthoracic echo; Ultrasound imaging; Ultrasound phantom.

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Conflict of interest statement

Conflict of interest disclosure Conavi Medical (Toronto, ON, Canada) is a medical device company that makes ultrasound probes to guide cardiovascular procedures. B.K.C. is a co-founder and CEO of Conavi Medical and has significant equity in the company. B.K.C. and B.N. receive employment income from Conavi Medical. B.K.C. and N.A. have contributed to patented inventions licensed to Conavi Medical and have royalty rights. Conavi Medical has provided partial cash and in-kind support for this study.

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