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Review
. 2020 Sep;75(9):1215-1222.
doi: 10.1111/anae.15100. Epub 2020 May 19.

The rise of organ donation after circulatory death: a narrative review

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Free article
Review

The rise of organ donation after circulatory death: a narrative review

D Gardiner et al. Anaesthesia. 2020 Sep.
Free article

Abstract

Solid organ transplantation saves and transforms lives. The original type of organ donation from deceased patients was controlled donation after circulatory death, previously referred to as non-heart beating organ donation. The rise of donation after circulatory death in the UK came about through advances in critical care and transplant medicine and support from several key organisations in developing a robust ethical, legal and professional framework. The transplant waiting list reached a historic peak in 2009-2010 of 8000 patients, but fell by 25% to 6000 in 2017-2018. There has also been a steady rise in the number of deceased donors and the number of donations after circulatory death. The contribution of donation after circulatory death to the total number of donations rose steadily between 2000 and 2012 and has remained about 40% since. Although the situation has improved for patients waiting for a transplant, deaths and long waits remain common. Changes to legislative, technical and peri-mortem procedures may greatly change future practices in donation after circulatory death in the UK.

Keywords: circulatory death; donation; ethics; transplantation.

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References

    1. Ridley S, Bonner S, Bray K, Falvey S, Mackay J, Manara A. UK guidance for non-heart-beating donation. British Journal of Anaesthesia 2005; 95: 592-5.
    1. Machado C. The first organ transplant from a brain-dead donor. Neurology 2005; 64: 1938-42.
    1. Machado C, Korein J, Ferrer Y, Portela L, de la C Garcia M, Manero JM. The concept of brain death did not evolve to benefit organ transplants. Journal of Medical Ethics 2007; 33: 197-200.
    1. NHS Blood and Transplant. Organ Donation and Transplantation annual activity report.. 2020. https://www.odt.nhs.uk/statistics-and-reports/annual-activity-report/ (accessed 20/03/2020).
    1. Lomero M, Gardiner D, Coll E, et al. Donation after circulatory death today: an updated overview of the European landscape. Transplant International 2020; 33: 76-88.

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