Bone disease in chronic pancreatitis
- PMID: 32432135
- PMCID: PMC7211537
- DOI: 10.12998/wjcc.v8.i9.1574
Bone disease in chronic pancreatitis
Abstract
Bone disease (osteopenia or osteoporosis) is a highly prevalent condition in society and presents a tremendous, preventable public health burden. Screening procedures, such as, dual-energy X-ray absorptiometry scans, have allowed early identification and intervention to improve bone health, and reduce the risk of osteoporotic fractures, which carry significant morbidity and mortality. The association of bone disease has been recognized in several diseases of the gastrointestinal tract, resulting in established guidelines for screening in patients with malabsorptive disorders such as inflammatory bowel disease and celiac disease. Increasingly, the risk of bone disease has been recognized in patients with chronic pancreatitis (CP), who share similar risk factors as patients with other high gastrointestinal disorders. As a result, there have been a number of studies examining the prevalence and risks of bone disease and fractures in patients with CP. This review aims to summarize the recent literature and current recommendations related to bone disease in CP.
Keywords: Bone disease; Chronic pancreatitis; Fracture risk; Malabsorption; Osteopenia; Osteoporosis.
©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Conflict of interest statement
Conflict-of-interest statement: Authors declare no conflict of interests for this article.
Similar articles
-
Burden of bone disease in chronic pancreatitis: A systematic review and meta-analysis.World J Gastroenterol. 2023 Feb 28;29(8):1374-1394. doi: 10.3748/wjg.v29.i8.1374. World J Gastroenterol. 2023. PMID: 36925454 Free PMC article.
-
Utilization of DXA Bone Mineral Densitometry in Ontario: An Evidence-Based Analysis.Ont Health Technol Assess Ser. 2006;6(20):1-180. Epub 2006 Nov 1. Ont Health Technol Assess Ser. 2006. PMID: 23074491 Free PMC article.
-
Chronic Pancreatitis and Bone Disease.J Clin Densitom. 2020 Apr-Jun;23(2):237-243. doi: 10.1016/j.jocd.2019.08.004. Epub 2019 Aug 22. J Clin Densitom. 2020. PMID: 31558406 Review.
-
Low Bone Mineral Density and Risk for Osteoporotic Fractures in Patients with Chronic Pancreatitis.Nutrients. 2021 Jul 13;13(7):2386. doi: 10.3390/nu13072386. Nutrients. 2021. PMID: 34371899 Free PMC article.
-
Bone health assessment in clinical practice is infrequenty performed in patients with chronic pancreatitis.Pancreatology. 2020 Sep;20(6):1109-1114. doi: 10.1016/j.pan.2020.07.396. Epub 2020 Jul 25. Pancreatology. 2020. PMID: 32826169 Free PMC article.
Cited by
-
Post-pancreatitis diabetes mellitus: insight on optimal management with nutrition and lifestyle approaches.Ann Med. 2022 Dec;54(1):1776-1786. doi: 10.1080/07853890.2022.2090601. Ann Med. 2022. PMID: 35786076 Free PMC article. Review.
-
The Risk of Fractures in Primary Hyperparathyroidism: A Meta-Analysis.JBMR Plus. 2021 Mar 16;5(4):e10482. doi: 10.1002/jbm4.10482. eCollection 2021 Apr. JBMR Plus. 2021. PMID: 33869997 Free PMC article.
-
Burden of bone disease in chronic pancreatitis: A systematic review and meta-analysis.World J Gastroenterol. 2023 Feb 28;29(8):1374-1394. doi: 10.3748/wjg.v29.i8.1374. World J Gastroenterol. 2023. PMID: 36925454 Free PMC article.
-
Does Chronic Pancreatitis in Growing Pigs Lead to Articular Cartilage Degradation and Alterations in Subchondral Bone?Int J Mol Sci. 2024 Feb 6;25(4):1989. doi: 10.3390/ijms25041989. Int J Mol Sci. 2024. PMID: 38396667 Free PMC article.
-
Sarcopenia in Chronic Pancreatitis - Prevalence, Diagnosis, Mechanisms and Potential Therapies.Curr Gastroenterol Rep. 2022 Apr;24(4):53-63. doi: 10.1007/s11894-022-00837-6. Curr Gastroenterol Rep. 2022. PMID: 35167003 Review.
References
-
- International Osteoporosis Foundation. Facts and Statistics. Cited 30 December 2019. Available from: URL: https://www.iofbonehealth.org/facts-statistics.
-
- Kanis JA, Borgstrom F, Zethraeus N, Johnell O, Oden A, Jönsson B. Intervention thresholds for osteoporosis in the UK. Bone. 2005;36:22–32. - PubMed
-
- Sambrook P, Cooper C. Osteoporosis. Lancet. 2006;367:2010–2018. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Research Materials
Miscellaneous