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Case Reports
. 2020 Jul;45(7):561-562.
doi: 10.1097/RLU.0000000000003081.

Incidental Finding of Colon Carcinoma Related to High Uptake in 18F-PSMA-1007 PET

Ayça Arçay, Matthias Eiber  1 , Thomas Langbein  1
Affiliations
Case Reports

Incidental Finding of Colon Carcinoma Related to High Uptake in 18F-PSMA-1007 PET

Ayça Arçay et al. Clin Nucl Med. 2020 Jul.

Abstract

We present a 78-year-old man with suspicion of prostate cancer due to a PSA of 200 ng/mL, who underwent F-PSMA-1007 (prostate specific membrane antigen) PET/CT for primary staging. Besides heterogeneous uptake to the prostate, an increased PSMA uptake in the cecum was observed, located in the thickened cecal wall with suspicion of a secondary malignancy. Colonoscopic biopsy followed by hemicolectomy confirmed the diagnosis of colon adenocarcinoma. This case demonstrates the importance of bioptic workup of suspicious findings on PSMA PET/CT, which are unlikely to be related to prostate cancer as PSMA ligand uptake is not exclusively prostate cancer specific.

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References

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