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Case Reports
. 2020 Jul;45(7):538-539.
doi: 10.1097/RLU.0000000000003059.

18F-FDG PET/CT in Sporadic Creutzfeldt-Jakob Disease

Ghali Zizi  1 , Henri Berger  2 , Paul Lalire  1 , Sébastien Dejust  1 , David Morland
Affiliations
Case Reports

18F-FDG PET/CT in Sporadic Creutzfeldt-Jakob Disease

Ghali Zizi et al. Clin Nucl Med. 2020 Jul.

Abstract

We report the case of a 64-year-old man referred for optic ataxia, constructional apraxia, and spatial orientation disorders evolving for 2 months. Benson syndrome (posterior cortical atrophy) was initially suspected. Brain F-FDG PET/CT depicted an asymmetric decreased uptake pattern consistent with Creutzfeldt-Jakob disease. 14-3-3 proteins were detected in the cerebrospinal fluid. Clinical evolution was quickly unfavorable. The patient died 1 month after the PET/CT, and Creutzfeldt-Jakob disease was confirmed on postmortem examination of brain tissue.

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References

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