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. 2021 Mar;28(2):58-64.
doi: 10.1136/ejhpharm-2019-002081. Epub 2020 Apr 21.

Automation of in-hospital pharmacy dispensing: a systematic review

Affiliations

Automation of in-hospital pharmacy dispensing: a systematic review

Sarah Batson et al. Eur J Hosp Pharm. 2021 Mar.

Abstract

Objectives: The current systematic review (SR) was undertaken to identify and summarise the published literature reporting on the clinical and economic value of automated in-hospital pharmacy services with a primary focus on systems supporting the dispensing of medicines.

Methods: Literature searches were conducted in MEDLINE, Embase and the Cochrane Library on 17 December 2017 to identify English-language publications investigating any automated dispensing systems (ADSs) in the inpatient setting to include central pharmacy and ward-based systems.

Results: 4320 publications were screened by title and abstract and 45 of 175 full publications screened were included. Grey literature searching identified an additional three publications. Therefore, 48 publications relating to ADSs were eligible for inclusion. Although a relatively large evidence base was identified as part of the current SR, the eligible studies were inconsistent in terms of their design and the format of reporting of outcomes. The studies demonstrate that both pharmacy and ward-based ADSs offer benefits over traditional manual dispensing methods in terms of clinical and economic outcomes. The primary benefits following implementation of an ADS include reductions in medication errors, medication administration time and costs. Studies examining optimisation/inventory management strategies/refill programmes for these systems suggest that optimal implementation of the ADS is required to ensure that clinical success and economic benefits are maximised.

Conclusions: The published evidence suggests positive impacts of ADS and should encourage hospitals to invest in automation, with a global strategy to improve the reliability and the efficiency of the medication process. However, one of the key findings of the current SR is the need for further data from adequately powered studies reporting clinically relevant outcomes which would allow for robust, evidence-based recommendations on the return on investment of the technologies. These studies would probably contribute to a larger adoption of these technologies by European hospitals.

Keywords: clinical pharmacy; dispensing forms; dispensing robots; hospital pharmacy automation; uni dose system.

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Conflict of interest statement

Competing interests: PB and AH report personal fees from Becton Dickinson, outside the submitted work. SB and SAM of Mtech Access were paid consultants to BD.

Figures

Figure 1
Figure 1
PRISMA flow diagram. BCMA, bar-code medication administration; CPOE, computerised physician order entry.

References

    1. Allard J, Carthey J, Cope J, et al. . Medication errors: causes, prevention and reduction. Br J Haematol 2002;116:255–65. 10.1046/j.1365-2141.2002.03272.x - DOI - PubMed
    1. Aldhwaihi K, Schifano F, Pezzolesi C, et al. . A systematic review of the nature of dispensing errors in hospital pharmacies. Integr Pharm Res Pract 2016;5:1–10. 10.2147/IPRP.S95733 - DOI - PMC - PubMed
    1. Cheung K-C, Bouvy ML, De Smet PAGM. Medication errors: the importance of safe dispensing. Br J Clin Pharmacol 2009;67:676–80. 10.1111/j.1365-2125.2009.03428.x - DOI - PMC - PubMed
    1. Lewis PJ, Dornan T, Taylor D, et al. . Prevalence, incidence and nature of prescribing errors in hospital inpatients: a systematic review. Drug Saf 2009;32:379–89. 10.2165/00002018-200932050-00002 - DOI - PubMed
    1. Berdot S, Gillaizeau F, Caruba T, et al. . Drug administration errors in hospital inpatients: a systematic review. PLoS One 2013;8:e68856. 10.1371/journal.pone.0068856 - DOI - PMC - PubMed

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