Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2020 Jul;24(3):282-289.
doi: 10.1111/hdi.12845. Epub 2020 May 20.

Hemodialysis treatment in patients with severe electrolyte disorders: Management of hyperkalemia and hyponatremia

Markus Pirklbauer  1
Affiliations
Review

Hemodialysis treatment in patients with severe electrolyte disorders: Management of hyperkalemia and hyponatremia

Markus Pirklbauer. Hemodial Int. 2020 Jul.

Abstract

Significant deviations of serum potassium and sodium levels are frequently observed in hospitalized patients and are both associated with increased all-cause and cardiovascular mortality. The presence of acute or chronic renal failure facilitates the pathogenesis and complicates the clinical management. In the absence of reliable outcome data in the context of dialysis prescription, requirement of renal replacement therapy in patients with severe electrolyte disturbances constitutes a therapeutic challenge. Recommendations for intradialytic management are based on pathophysiologic reasoning and clinical observations only, and as such, heterogeneous and limited to expert opinion level. This article reviews current strategies for the management of severe hyperkalemia and hyponatremia in hemodialysis patients.

Keywords: Hemodialysis; hyperkalemia; hyponatremia.

PubMed Disclaimer

References

    1. Abuelo JG. Treatment of severe hyperkalemia: Confronting 4 fallacies. Kidney Int Rep. 2018;3:47–55. - PMC - PubMed
    1. An JN, Lee JP, Jeon HJ, et al. Severe hyperkalemia requiring hospitalization: Predictors of mortality. Crit Care. 2012;16:R225. - PMC - PubMed
    1. Kovesdy CP, Regidor DL, Mehrotra R, et al. Serum and dialysate potassium concentrations and survival in hemodialysis patients. Clin J Am Soc Nephrol. 2007;2:999–1007. - PubMed
    1. Lin J, Cheng Z, Ding X, Qian Q. Acid–base and electrolyte managements in chronic kidney disease and end‐stage renal disease: Case‐based discussion. Blood Purif. 2018;45:179–186. - PubMed
    1. Daugirdas J, Blake P, Ing T. Handbook of Dialysis. 5th ed. Philadelphia, PA: Wolters Kluwer Health, 2015.

MeSH terms