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Review
. 2020 Jun;13(6):e008688.
doi: 10.1161/CIRCEP.120.008688. Epub 2020 May 21.

Use of Chloroquine and Hydroxychloroquine in COVID-19 and Cardiovascular Implications: Understanding Safety Discrepancies to Improve Interpretation and Design of Clinical Trials

Affiliations
Review

Use of Chloroquine and Hydroxychloroquine in COVID-19 and Cardiovascular Implications: Understanding Safety Discrepancies to Improve Interpretation and Design of Clinical Trials

Ohad Oren et al. Circ Arrhythm Electrophysiol. 2020 Jun.
No abstract available

Keywords: COVID-19; chloroquine; hydroxychloroquine; pandemic; trophozoites.

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Figures

Figure.
Figure.
Systemic adverse effects of chloroquine and hydroxychloroquine.

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References

    1. Dong E, Du H, Gardner L. An interactive web-based dashboard to track COVID-19 in real time. Lancet Infect Dis. 2020;20:533–534. doi: 10.1016/S1473-3099(20)30120-1. - PMC - PubMed
    1. Rolain JM, Colson P, Raoult D. Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century. Int J Antimicrob Agents. 2007;30:297–308. doi: 10.1016/j.ijantimicag.2007.05.015. - PMC - PubMed
    1. Sullivan DJ, Jr, Gluzman IY, Russell DG, Goldberg DE. On the molecular mechanism of chloroquine’s antimalarial action. Proc Natl Acad Sci U S A. 1996;93:11865–11870. doi: 10.1073/pnas.93.21.11865. - PMC - PubMed
    1. Vincent MJ, Bergeron E, Benjannet S, Erickson BR, Rollin PE, Ksiazek TG, Seidah NG, Nichol ST. Chloroquine is a potent inhibitor of SARS coronavirus infection and spread. Virol J. 2005;2:69. doi: 10.1186/1743-422X-2-69. - PMC - PubMed
    1. Yao X, Ye F, Zhang M, Cui C, Huang B, Niu P, Liu X, Zhao L, Dong E, Song C, et al. In vitroantiviralactivity and projection of optimizeddosingdesign of hydroxychloroquine for the treatment of severeacuterespiratorysyndromecoronavirus 2 (SARS-CoV-2). Clin Infect Dis. 2020:ciaa237. doi: 10.1093/cid/ciaa237. - PMC - PubMed

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