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Editorial
. 2020 Jul 1;202(1):8-10.
doi: 10.1164/rccm.202005-1651ED.

COVID-19, Asthma, and Inhaled Corticosteroids: Another Beneficial Effect of Inhaled Corticosteroids?

Tania Maes  1 , Ken Bracke  1 , Guy G Brusselle  1   2
Affiliations
Editorial

COVID-19, Asthma, and Inhaled Corticosteroids: Another Beneficial Effect of Inhaled Corticosteroids?

Tania Maes et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
ACE2 (angiotensin-converting enzyme 2) mRNA expression in human lung tissue and effect of ICS. (A) ACE2 gene expression in lung tissue from controls (n = 61), asthma/ACO (n = 7), and COPD (Global Initiative for Chronic Obstructive Lung Disease [GOLD] stage II) (n = 38). (B) ACE2 gene expression in controls (no OAD, no ICS use, n = 56), in subjects with OAD not using ICS (n = 23) and in subjects with OAD using ICS (n = 25). Lung resection samples were obtained with approval from the ethical committee of Ghent University Hospital (2016/0132); all participants provided written informed consent. Processing for RNA and quantitative RT-PCR analysis was performed as described previously (14, 15). ACE2 mRNA expression was normalized to the expression of three reference genes. ACO = asthma–COPD overlap; COPD = chronic obstructive pulmonary disease; ICS = inhaled corticosteroids; OAD = obstructive airway diseases (asthma, ACO, or COPD).
See this image and copyright information in PMC

Comment in

  • Inhaled Corticosteroids and COVID-19.
    Lipworth B, Kuo CR, Lipworth S, Chan R. Lipworth B, et al. Am J Respir Crit Care Med. 2020 Sep 15;202(6):899-900. doi: 10.1164/rccm.202005-2000LE. Am J Respir Crit Care Med. 2020. PMID: 32668178 Free PMC article. No abstract available.

Comment on

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