Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Sep;18(10):2366-2368.e3.
doi: 10.1016/j.cgh.2020.05.011. Epub 2020 May 11.

COVID-19 Digestive System Involvement and Clinical Outcomes in a Large Academic Hospital in Milan, Italy

Alessio Aghemo  1 , Daniele Piovani  2 , Tommaso Lorenzo Parigi  3 , Enrico Brunetta  4 , Nicola Pugliese  3 , Edoardo Vespa  3 , Paolo Dario Omodei  5 , Paoletta Preatoni  5 , Ana Lleo  6 , Alessandro Repici  7 , Antonio Voza  8 , Maurizio Cecconi  9 , Alberto Malesci  10 , Stefanos Bonovas  2 , Silvio Danese  2 ; Humanitas COVID-19 Task Force
Affiliations

COVID-19 Digestive System Involvement and Clinical Outcomes in a Large Academic Hospital in Milan, Italy

Alessio Aghemo et al. Clin Gastroenterol Hepatol. 2020 Sep.

Abstract

Since February 2020, the COVID-19 pandemic has spread to Italy affecting more than 100,000 people. Several studies have reported a high prevalence of gastrointestinal (GI) symptoms, and investigated their potential association with clinical outcomes.1 The timing, clinical significance, and possible impact on viral spread of GI symptoms presentation have not been fully elucidated. Elevation of liver function tests and other laboratory values has also been reported; however, their prognostic significance has not been clearly established.2.

PubMed Disclaimer

References

    1. Zhou Z, Zhao N, Shu Y, et al. Journal pre-proof effect of gastrointestinal symptoms on patients infected with COVID-19. 2020. Available at: 10.1053/j.gastro.2020.03.020. Accessed April 6, 2020. - DOI
    1. Zhang C., Shi L., Wang F. Liver injury in COVID-19: management and challenges. Lancet. 2020;10:2019–2021. doi: 10.1016/S2468-1253(20)30057-1. Available at: - DOI - PMC - PubMed
    1. Cecconi M., Piovani D., Brunetta E. Early predictors of clinical deterioration in a cohort of 239 patients hospitalized for COVID-19 infection in Lombardy, Italy. J Clin Med. 2020;9:E1548. - PMC - PubMed
    1. Xiao F., Tang M., Zheng X. Evidence for gastrointestinal infection of SARS-CoV-2. Gastroenterology. 2020 http://www.ncbi.nlm.nih.gov/pubmed/32142773 Available at: - PMC - PubMed
    1. Cheung K.S., Hung I.F., Chan P.P. Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from the Hong Kong Cohort and systematic review and meta-analysis. Gastroenterology. 2020 pii:S0016-5085(20)30448-0. - PMC - PubMed