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Review
. 2020 Jun;43(2):331-344.
doi: 10.1016/j.psc.2020.02.006. Epub 2020 Apr 8.

Frontotemporal Dementia: Neuropathology, Genetics, Neuroimaging, and Treatments

Kyan Younes  1 , Bruce L Miller  2
Affiliations
Review

Frontotemporal Dementia: Neuropathology, Genetics, Neuroimaging, and Treatments

Kyan Younes et al. Psychiatr Clin North Am. 2020 Jun.

Abstract

Frontotemporal dementia (FTD) encompasses a group of clinical syndromes, including behavioral variant FTD, nonfluent variant primary progressive aphasia, semantic variant primary progressive aphasia, FTD motor neuron disease, progressive supranuclear palsy syndrome, and corticobasal syndrome. Early on in its course, FTD is commonly seen in psychiatric clinics. In this article the authors review the neuroimaging, pathology, genetics, and therapeutic interventions for FTD spectrum disorders.

Keywords: Frontotemporal dementia; Genetics; Neuroimaging; Neuropathology.

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Conflict of interest statement

Disclosure K. Younes has no financial disclosures. B.L. Miller is supported by NIHgrants: P30AG062422, P01AG019724, T32 AG023481.

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