ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer
- PMID: 32439716
- PMCID: PMC7295852
- DOI: 10.1136/esmoopen-2020-000793
ESMO Management and treatment adapted recommendations in the COVID-19 era: Breast Cancer
Abstract
The global preparedness and response to the rapid escalation to severe acute respiratory syndrome coronavirus (SARS-CoV)-2-related disease (COVID-19) to a pandemic proportion has demanded the formulation of a reliable, useful and evidence-based mechanism for health services prioritisation, to achieve the highest quality standards of care to all patients. The prioritisation of high value cancer interventions must be embedded in the agenda for the pandemic response, ensuring that no inconsistency or discrepancy emerge in the health planning processes.The aim of this work is to organise health interventions for breast cancer management and research in a tiered framework (high, medium, low value), formulating a scheme of prioritisation per clinical cogency and intrinsic value or magnitude of benefit. The public health tools and schemes for priority setting in oncology have been used as models, aspiring to capture clinical urgency, value in healthcare, community goals and fairness, while respecting the principles of benevolence, non-maleficence, autonomy and justice.We discuss the priority health interventions across the cancer continuum, giving a perspective on the role and meaning to maintain some services (undeferrable) while temporarily abrogate some others (deferrable). Considerations for implementation and the essential link to pre-existing health services, especially primary healthcare, are addressed, outlining a framework for the development of effective and functional services, such as telemedicine.The discussion covers the theme of health systems strategising, and why oncology care, in particular breast cancer care, should be maintained in parallel to pandemic control measures, providing a pragmatic clinical model within the broader context of public healthcare schemes.
Keywords: COVID-19; ESMO adapted recommendations; breast cancer.
© Author (s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. Published by BMJ on behalf of the European Society for Medical Oncology.
Conflict of interest statement
Competing interests: GC has received honoraria from Pfizer, Novartis, Eli Lilly, Roche; fees for expert testimony and medical education from Pfizer and has participated in advisory boards for Pfizer, Roche, Eli Lilly, Novartis, Seattle Genetics, Celltrion. SD reports grants, institutional fees from Roche/Genentech, Pfizer, Puma, AstraZeneca, Novartis, Amgen, Sanofi, Eli Lilly, MSD, BMS, Daichi and non-financial support from Roche/Genentech, Pfizer, AstraZeneca. SDC has received fees for medical education from Novartis and Pierre-Fabre and is the recipient of the IG 20774 of Fondazione AIRC. MG reports personal fees/travel support from Amgen, AstraZeneca, Celgene, Eli Lilly, Invectys, Pfizer, Novartis, Puma, Nanostring, Roche, Medison, LifeBrain, all outside the submitted work; an immediate family member is employed by Sandoz. PP is medical advisor of Sordina IORT Technologies. ES has received honoraria from Amgen, AstraZeneca, Clinigen, Egis, Eli Lilly, Genomic Health, Novartis, Pfizer, Pierre-Fabre, Roche, Sandoz, TLC Biopharmaceuticals and travel support from Amgen, AstraZeneca, Egis, Novartis, Pfizer, Roche. FC has consultancy role for Amgen, Astellas/Medivation, AstraZeneca, Celgene, Daiichi-Sankyo, Eisai, GE Oncology, Genentech, GlaxoSmithKline, Macrogenics, Medscape, Merck-Sharp, Merus BV, Mylan, Mundipharma, Novartis, Pfizer, Pierre-Fabre, prIME Oncology, Roche, Sanofi, Samsung Bioepis, Seattle Genetics, Teva. EdA honoraria and/or advisory board from Roche/GNE, Novartis, SeaGen and Zodiac; travel grants from Roche/GNE and GSK/Novartis; research grant to the institution from Roche/GNE, AstraZeneca, GSK/Novartis and Servier. CC declares consultancy/advisory role/speaker's bureau: Pfizer, Eli Lilly, Roche, Novartis. SP-S discloses honoraria, consultancy and speaker’s bureau: Roche, Novartis, Pfizer, Eli Lilly, AstraZeneca, Nanostring.
Figures
Similar articles
-
ESMO management and treatment adapted recommendations in the COVID-19 era: gynaecological malignancies.ESMO Open. 2020 Jul;5(Suppl 3):e000827. doi: 10.1136/esmoopen-2020-000827. ESMO Open. 2020. PMID: 32718919 Free PMC article. Review.
-
ESMO management and treatment adapted recommendations in the COVID-19 era: colorectal cancer.ESMO Open. 2020 May;5(Suppl 3):e000826. doi: 10.1136/esmoopen-2020-000826. ESMO Open. 2020. PMID: 32457036 Free PMC article. Review.
-
ESMO Management and treatment adapted recommendations in the COVID-19 era: Pancreatic Cancer.ESMO Open. 2020 May;5(Suppl 3):e000804. doi: 10.1136/esmoopen-2020-000804. ESMO Open. 2020. PMID: 32423899 Free PMC article. Review.
-
ESMO Management and treatment adapted recommendations in the COVID-19 era: Lung cancer.ESMO Open. 2020 Jun;5(Suppl 3):e000820. doi: 10.1136/esmoopen-2020-000820. ESMO Open. 2020. PMID: 32581069 Free PMC article.
-
Recommendations for prioritization, treatment, and triage of breast cancer patients during the COVID-19 pandemic. the COVID-19 pandemic breast cancer consortium.Breast Cancer Res Treat. 2020 Jun;181(3):487-497. doi: 10.1007/s10549-020-05644-z. Epub 2020 Apr 24. Breast Cancer Res Treat. 2020. PMID: 32333293 Free PMC article.
Cited by
-
Cancer surgery in the era of COVID-19 pandemic: Changing dynamics.J Surg Oncol. 2020 Nov;122(6):1262-1263. doi: 10.1002/jso.26156. Epub 2020 Aug 5. J Surg Oncol. 2020. PMID: 32761619 Free PMC article. No abstract available.
-
COVID-19 safe and fully operational radiotherapy: An AIRO survey depicting the Italian landscape at the dawn of phase 2.Radiother Oncol. 2021 Feb;155:120-122. doi: 10.1016/j.radonc.2020.09.049. Epub 2020 Oct 14. Radiother Oncol. 2021. PMID: 33065185 Free PMC article. No abstract available.
-
Breast Cancer and COVID-19: Challenges in Surgical Management.Cancers (Basel). 2022 Oct 31;14(21):5360. doi: 10.3390/cancers14215360. Cancers (Basel). 2022. PMID: 36358779 Free PMC article. Review.
-
A tripartite approach can seek to optimize breast cancer management during a pandemic - Real-Time experience of a developing breast oncology unit in Singapore.Breast J. 2020 Aug;26(8):1593-1596. doi: 10.1111/tbj.13961. Epub 2020 Jul 1. Breast J. 2020. PMID: 32608540 Free PMC article. No abstract available.
-
Safety of adjuvant CDK4/6 inhibitors during the COVID-19 pandemic.Lancet Oncol. 2022 Feb;23(2):195-197. doi: 10.1016/S1470-2045(21)00708-7. Lancet Oncol. 2022. PMID: 35114114 Free PMC article. No abstract available.
References
-
- Burki T.K. Cancer guidelines during the COVID-19 pandemic. Lancet Oncol. 2020;21:629–630. doi:10.1016/S1470-2045(20)30217-5 - DOI - PMC - PubMed
-
- Emanuel E.J., Persad G., Upshur R. Fair allocation of scarce medical resources in the time of Covid-19. N Engl J Med. 2020 http://www.ncbi.nlm.nih.gov/pubmed/32202722 doi:10.1056/NEJMsb2005114 doi [Epub ahead of print 23 Mar 2020] - DOI - PubMed
-
- Baker T., Schell C.O., Petersen D.B. Essential care of critical illness must not be forgotten in the COVID-19 pandemic. Lancet. 2020;395:1253–1254. http://www.ncbi.nlm.nih.gov/pubmed/32246914 doi:10.1016/S0140-6736(20)30793-5 - DOI - PMC - PubMed
-
- GBD 2016 Healthcare Access and Quality Collaborators Measuring performance on the healthcare access and quality index for 195 countries and territories and selected subnational locations: a systematic analysis from the global burden of disease study 2016. Lancet. 2018;391:2236–2271. http://www.ncbi.nlm.nih.gov/pubmed/29893224 doi:10.1016/S0140-6736(18)30994-2 - DOI - PMC - PubMed
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous