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. 2020 Aug;43(8):854-856.
doi: 10.1038/s41440-020-0476-3. Epub 2020 May 22.

Downregulation of ACE2 induces overstimulation of the renin-angiotensin system in COVID-19: should we block the renin-angiotensin system?

François Silhol  1 , Gabrielle Sarlon  2 , Jean-Claude Deharo  2 , Bernard Vaïsse  2
Affiliations

Downregulation of ACE2 induces overstimulation of the renin-angiotensin system in COVID-19: should we block the renin-angiotensin system?

François Silhol et al. Hypertens Res. 2020 Aug.
No abstract available

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Conflict of interest statement

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Renin–angiotensin system (RAS) regulation
Fig. 2
Fig. 2
Downregulation of ACE2 during COVID-19 increases AT1R stimulation, hypokalemia, and lung and cardiovascular injury (FS)
See this image and copyright information in PMC

References

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