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Review
. 2020 Jul 10;38(20):2341-2350.
doi: 10.1200/JCO.19.02896. Epub 2020 May 22.

Breast Cancer-Related Lymphedema: Risk Factors, Screening, Management, and the Impact of Locoregional Treatment

Sarah A McLaughlin  1 , Cheryl L Brunelle  2   3 , Alphonse Taghian  2   4
Affiliations
Review

Breast Cancer-Related Lymphedema: Risk Factors, Screening, Management, and the Impact of Locoregional Treatment

Sarah A McLaughlin et al. J Clin Oncol. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the National Cancer Institute or the National Institutes of Health.

Figures

FIG 1.
FIG 1.
Semiannual hazard rate for development of breast cancer–related lymphedema for the entire cohort and by axillary surgery and radiation groups. ALND, axillary lymph node dissection; RLNR, regional lymph node radiation; SLNB, sentinel lymph node biopsy. Reprinted from McDuff et al, with permission of Elsevier.
FIG 2.
FIG 2.
Histogram of baseline arm asymmetry. Magnitude of baseline asymmetry > 5% and > 10% is shaded; 28.3% and 2.9% of the study cohort have magnitude of baseline asymmetry > 5% and > 10%, respectively. Reprinted from Sun et al, by permission from Springer Nature.
FIG 3.
FIG 3.
Relative arm volume change corresponding to arm volume increase by 200 mL in the unaffected arm of 677 patients. Reprinted from Ancukiewicz et al, by permission from Springer Nature.
FIG 4.
FIG 4.
Common objective measurement tools for breast cancer–related lymphedema screening: bioimpedance spectroscopy (SOZO Bioimpedance Spectroscopy Device; ImpediMed, Carlsbad, CA). Copyright © ImpediMed Limited and ImpediMed, Perometry, Girth Measures.
See this image and copyright information in PMC

References

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    1. Shaitelman SF, Chiang Y-J, Griffin KD, et al. Radiation therapy targets and the risk of breast cancer-related lymphedema: A systematic review and network meta-analysis. Breast Cancer Res Treat. 2017;162:201–215. - PubMed
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