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Practice Guideline
. 2020 Jun;135(6):e261-e274.
doi: 10.1097/AOG.0000000000003893.

Thyroid Disease in Pregnancy: ACOG Practice Bulletin, Number 223

No authors listed
Practice Guideline

Thyroid Disease in Pregnancy: ACOG Practice Bulletin, Number 223

No authors listed. Obstet Gynecol. 2020 Jun.

Abstract

Both thyrotoxicosis and hypothyroidism are associated with adverse pregnancy outcomes. There also is concern about the effect of overt maternal thyroid disease on fetal development. In addition, medications that affect the maternal thyroid gland can cross the placenta and affect the fetal thyroid gland. This document reviews the thyroid-related pathophysiologic changes that occur during pregnancy and the effects of overt and subclinical maternal thyroid disease on maternal and fetal outcomes. This Practice Bulletin has been updated with information on the diagnosis and the management of thyroid disease in pregnant women and includes a new clinical algorithm on management of thyroid disease in pregnancy.

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References

    1. Vannucchi G, Covelli D, Vigo B, Perrino M, Mondina L, Fugazzola L. Thyroid volume and serum calcitonin changes during pregnancy. J Endocrinol Invest 2017;40:727–32. (Level II-3)
    1. Huang SA. Physiology and pathophysiology of type 3 deiodinase in humans. Thyroid 2005;15:875–81. (Level III)
    1. Alexander EK, Pearce EN, Brent GA, Brown RS, Chen H, Dosiou C, et al. 2017 guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and the postpartum [published erratum appears in Thyroid 2017;27:1212]. Thyroid 2017;27:315–89. (Level III)
    1. Ross DS, Burch HB, Cooper DS, Greenlee MC, Laurberg P, Maia AL, et al. 2016 American Thyroid Association guidelines for diagnosis and management of hyperthyroidism and other causes of thyrotoxicosis [published erratum appears in Thyroid 2017;27:1462]. Thyroid 2016;26:1343–421. (Level III)
    1. Bernal J. Thyroid hormone receptors in brain development and function. Nat Clin Pract Endocrinol Metab 2007;3:249–59. (Level III)

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