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. 2020 May 18;12(5):553.
doi: 10.3390/v12050553.

Seroprevalence of Dromedary Camel HEV in Domestic and Imported Camels from Saudi Arabia

Sherif Aly El-Kafrawy  1   2   3 , Ahmed Mohamed Hassan  1   2 , Mai Mohamed El-Daly  2   3 , Ishtiaq Qadri  1 , Ahmed Majdi Tolah  2 , Tagreed Lafi Al-Subhi  2 , Abdulrahman A Alzahrani  4 , Ghaleb A Alsaaidi  4 , Nabeela Al-Abdullah  2   5   6 , Reham Mohammed Kaki  2   6   7 , Tian-Cheng Li  8 , Esam Ibraheem Azhar  2   3
Affiliations

Seroprevalence of Dromedary Camel HEV in Domestic and Imported Camels from Saudi Arabia

Sherif Aly El-Kafrawy et al. Viruses. .

Abstract

Hepatitis E Virus (HEV) imposes a major health concern in areas with very poor sanitation in Africa and Asia. The pathogen is transmitted mainly through ingesting contaminated water or food, coming into contact with affected people, and blood transfusions. Very few reports including old reports are available on the prevalence of HEV in Saudi Arabia in humans and no reports exist on HEV prevalence in camels. Dromedary camel trade and farming are increasing in Saudi Arabia with importation occurring unidirectionally from Africa to Saudi Arabia. DcHEV transmission to humans has been reported in one case from the United Arab Emeritus (UAE). This instigated us to perform this investigation of the seroprevalence of HEV in imported and domestic camels in Saudi Arabia. Serum samples were collected from imported and domestic camels. DcHEV-Abs were detected in collected sera using ELISA. The prevalence of DcHEV in the collected samples was 23.1% with slightly lower prevalence in imported camels than domestic camels (22.4% vs. 25.4%, p value = 0.3). Gender was significantly associated with the prevalence of HEV in the collected camels (p value = 0.015) where males (31.6%) were more infected than females (13.4%). This study is the first study to investigate the prevalence of HEV in dromedary camels from Saudi Arabia. The high seroprevalence of DcHEV in dromedaries might indicate their role as a zoonotic reservoir for viral infection to humans. Future HEV seroprevalence studies in humans are needed to investigate the role of DcHEV in the Saudi human population.

Keywords: DcHEV; Saudi Arabia; dromedary camels.

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Conflict of interest statement

The authors declare no conflict of interest.

References

    1. Balayan M.S., Andjaparidze A.G., Savinskaya S.S., Ketiladze E.S., Braginsky D.M., Savinov A.P., Poleschuk V.F. Evidence for a virus in non-A, non-B hepatitis transmitted via the fecal-oral route. Intervirology. 1983;20:23–31. - PubMed
    1. Cai Y., Qin S.-Y., Qian A., Xu P., Xu Y.-T., Xie L.-H., Zhao Q., Zhang X.-X. Seroprevalence and risk factors of hepatitis E virus infection among the Korean, Manchu, Mongol, and Han ethnic groups in Eastern and Northeastern China. J. Med. Virol. 2017;89:1988–1994. doi: 10.1002/jmv.24871. - DOI - PubMed
    1. Obaidat M.M., Roess A.A. Seroprevalence and risk factors of Hepatitis E infection in Jordan’s population: First report. Int. J. Infect. Dis. 2018;66:121–125. doi: 10.1016/j.ijid.2017.11.015. - DOI - PubMed
    1. Bricks G., Senise J.F., Pott Junior H., Grandi G., Passarini A., Caldeira D.B., Carnaúba Junior D., Moraes H.A.B.D., Granato C.F.H., Castelo A. Seroprevalence of hepatitis E virus in chronic hepatitis C in Brazil. Braz. J. Infect. Dis. 2018;22:85–91. doi: 10.1016/j.bjid.2018.02.001. - DOI - PMC - PubMed
    1. Grabarczyk P., Sulkowska E., Gdowska J., Kopacz A., Liszewski G., Kubicka-Russel D., Baylis S.A., Corman V.M., Noceń E., Piotrowski D., et al. Molecular and serological infection marker screening in blood donors indicates high endemicity of hepatitis E virus in Poland. Transfusion. 2018;58:1245–1253. doi: 10.1111/trf.14531. - DOI - PubMed

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