COVID-19 and the nicotinic cholinergic system
- PMID: 32444400
- PMCID: PMC7248130
- DOI: 10.1183/13993003.01589-2020
COVID-19 and the nicotinic cholinergic system
Abstract
The prevalence of smoking among hospitalised COVID-19 patients is low. COVID-19 manifestations could be linked to impairment of the cholinergic anti-inflammatory pathway. Nicotinic cholinergic agonists should be examined as potential therapeutic options.
Conflict of interest statement
Conflict of interest: K. Farsalinos has nothing to disclose. Conflict of interest: A. Angelopoulou has nothing to disclose. Conflict of interest: N. Alexandris has nothing to disclose. Conflict of interest: K. Poulas has nothing to disclose.
Comment in
-
Smoking, ACE-2 and COVID-19: ongoing controversies.Eur Respir J. 2020 Jul 16;56(1):2001759. doi: 10.1183/13993003.01759-2020. Print 2020 Jul. Eur Respir J. 2020. PMID: 32430431 Free PMC article.
Comment on
-
ACE-2 expression in the small airway epithelia of smokers and COPD patients: implications for COVID-19.Eur Respir J. 2020 May 14;55(5):2000688. doi: 10.1183/13993003.00688-2020. Print 2020 May. Eur Respir J. 2020. PMID: 32269089 Free PMC article.
References
-
- Farsalinos K, Barbouni A, Niaura R. Systematic review of the prevalence of current smoking among hospitalized COVID-19 patients in China: could nicotine be a therapeutic option? Intern Emerg Med 2020; in press [https://doi.org/10.1007/s11739-020-02355-7]. doi:10.1007/s11739-020-02355-7 - DOI - PMC - PubMed
-
- Centers for Disease Control and Prevention. Preliminary estimates of the prevalence of selected underlying health conditions among patients with coronavirus disease 2019 — United States, February 12–March 28, 2020. MMWR Morb Mortal Wkly Rep 2020; 69: 382–386. doi:10.15585/mmwr.mm6913e2 - DOI - PMC - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
Miscellaneous