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. 2020 Oct;79(10):1383-1386.
doi: 10.1136/annrheumdis-2020-217522. Epub 2020 May 22.

Antibodies against immunogenic epitopes with high sequence identity to SARS-CoV-2 in patients with autoimmune dermatomyositis

Spyridon Megremis  1 , Thomas D J Walker  2 , Xiaotong He  2 , William E R Ollier  3   4 , Hector Chinoy  5   6 , Lynne Hampson  2 , Ian Hampson  2 , Janine A Lamb  7
Affiliations

Antibodies against immunogenic epitopes with high sequence identity to SARS-CoV-2 in patients with autoimmune dermatomyositis

Spyridon Megremis et al. Ann Rheum Dis. 2020 Oct.
No abstract available

Keywords: autoantibodies; autoimmune diseases; dermatomyositis.

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Conflict of interest statement

Competing interests: JAL reports grants from The Myositis Association, grants from Medical Research Council (MR/N003322/1), during the conduct of the study; grants from MedImmune, outside the submitted work.

Figures

Figure 1
Figure 1
Coronavirus species and epitopes. (A) Taxonomy tree of coronavirus species identified in the study. The total number of next-generation sequencing (NGS) reads per species is visualised as red bar plots. Green squares: presence only in dermatomyositis (DM), squares with no filling: presence only in healthy controls (HC). (B) Partial alignments of the three bat coronavirus epitopes which are shared with SARS-CoV-2. SARS-CoV-2, severe acute respiratory syndrome coronavirus-2.
See this image and copyright information in PMC

Comment in

References

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