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. 2020 Jul 13;9(3):366-369.
doi: 10.1093/jpids/piaa065.

Dynamic Viral Severe Acute Respiratory Syndrome Coronavirus 2 RNA Shedding in Children: Preliminary Data and Clinical Consideration from a Italian Regional Center

Maria A De Ioris  1 , Alessia Scarselli  1 , Marta L Ciofi Degli Atti  2 , Lucilla Ravà  2 , Andrea Smarrazzo  1 , Carlo Concato  3 , Lorenza Romani  1 , Raffaella Scrocca  1 , Caterina Geremia  1 , Michaela Carletti  3 , Francesca I Calò Carducci  1 , Stefania Bernardi  1 , Luana Coltella  3 , Veronica Santilli  1 , Sara Chiurchiu  1 , Emanuela Peschiaroli  1 , Rosanna Mariani  1 , Caterina Marabotto  1 , Daniela Perrotta  4 , Alberto Villani  1 , Paolo Rossi  1 , Patrizia D'Argenio  1 , Andrea Campana  1 , Massimiliano Raponi  2
Affiliations

Dynamic Viral Severe Acute Respiratory Syndrome Coronavirus 2 RNA Shedding in Children: Preliminary Data and Clinical Consideration from a Italian Regional Center

Maria A De Ioris et al. J Pediatric Infect Dis Soc. .

Abstract

We evaluated severe acute respiratory syndrome coronavirus 2 RNA clearance in 22 children. The estimation of positivity at day 14 was 52% for nasopharyngeal swab and 31% for stool samples. These data underline the significance of nasopharyngeal and stoolsample for detecting infected children. Additional studies are needed for transmissibility.

Keywords: SARS-CoV-2; children; coronavirus; viral RNA shedding.

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Figures

Figure 1
Figure 1
Representation of viral RNA shedding from RF tract according to Kaplan-Meyer method. Day 0 represents the onset of symptoms. Asymptomatic patients were excluded from the Kaplan-Meier analysis. Abbreviation: RF, rhinopharyngeal.
Figure 2
Figure 2
Representation of viral RNA shedding in stool samples according to Kaplan-Meyer method. Day 0 represents the onset of symptoms. Asymptomatic patients were excluded from the Kaplan Meier analysis.
See this image and copyright information in PMC

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