Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2020 Sep;73(3):705-708.
doi: 10.1016/j.jhep.2020.05.013. Epub 2020 May 21.

High mortality rates for SARS-CoV-2 infection in patients with pre-existing chronic liver disease and cirrhosis: Preliminary results from an international registry

Andrew M Moon  1 , Gwilym J Webb  2 , Costica Aloman  3 , Matthew J Armstrong  4 , Tamsin Cargill  2 , Renumathy Dhanasekaran  5 , Joan Genescà  6 , Upkar S Gill  7 , Theodore W James  1 , Patricia D Jones  8 , Aileen Marshall  9 , George Mells  10 , Ponni V Perumalswami  11 , Xiaolong Qi  12 , Feng Su  13 , Nneka N Ufere  14 , Eleanor Barnes  2 , A Sidney Barritt  1 , Thomas Marjot  15
Affiliations
Comment

High mortality rates for SARS-CoV-2 infection in patients with pre-existing chronic liver disease and cirrhosis: Preliminary results from an international registry

Andrew M Moon et al. J Hepatol. 2020 Sep.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of interest The authors have no conflicts of interest or competing interests to disclose. Please refer to the accompanying ICMJE disclosure forms for further details.

Figures

Fig. 1
Fig. 1
Outcome in patients with non-cirrhotic chronic liver disease or cirrhosis with COVID-19. Graphs depict data from 152 submissions to COVID-Hep.net and COVIDCirrhosis.org registries between 25th March 2020 and 20th April 2020. (A) Case fatality rate by liver disease stage. (B) Rates of hepatic decompensation by stage of cirrhosis (defined as one or more of new or worsened ascites, spontaneous bacterial peritonitis, new or worsened hepatic encephalopathy, or variceal haemorrhage). p values derived using chi-squared test. CLD, chronic liver disease without cirrhosis; CP, Child-Pugh.
See this image and copyright information in PMC

Comment on

References

    1. Moon A.M., Singal A.G., Tapper E.B. Contemporary epidemiology of chronic liver disease and cirrhosis. Clin Gastroenterol Hepatol. 2019;(S1542–3565(19)) 30849–30844. - PMC - PubMed
    1. Albillos A., Lario M., Álvarez-Mon M. Cirrhosis-associated immune dysfunction: distinctive features and clinical relevance. J Hepatol. 2014;61(6):1385–1396. - PubMed
    1. Boettler T., Newsome P.N., Mondelli M.U., Maticic M., Cordero E., Cornberg M. Care of patients with liver disease during the COVID-19 pandemic: EASL-ESCMID position paper. JHEP Rep. 2020;2(3):100113. - PMC - PubMed
    1. Mehra M.R., Desai S.S., Kuy S., Henry T.D., Patel A.N. Cardiovascular disease, drug therapy, and mortality in Covid-19. N Engl J Med. 2020;(NEJMoa2007621) - PMC - PubMed
    1. Schmidt M.L., Barritt A.S., Orman E.S., Hayashi P.H. Decreasing mortality among patients hospitalized with cirrhosis in the United States from 2002 through 2010. Gastroenterology. 2015;148(5):967–977.e2. - PMC - PubMed