Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2021 Sep;26(5):1037-1062.
doi: 10.1007/s10741-020-09955-7.

Consensus document: management of heart failure in type 2 diabetes mellitus

Affiliations
Review

Consensus document: management of heart failure in type 2 diabetes mellitus

Upendra Kaul et al. Heart Fail Rev. 2021 Sep.

Abstract

Type 2 diabetes mellitus (T2DM) is a known predisposing factor for heart failure (HF). The growing burden of these two conditions and their impact on health of the individual and on society in general needs urgent attention from the health care professionals. Availability of multiple treatment choices for managing T2DM and HF may make therapeutic decisions more complex for clinicians. Recent cardiovascular outcome trials of antidiabetic drugs have added very robust evidence to effectively manage subjects with this dual condition. This consensus statement provides the prevalence trends and the impact of this dual burden on patients. In addition, it concisely narrates the types of HF, the different treatment algorithms, and recommendations for physicians to comprehensively manage such patients.

Keywords: Diagnosis; Drug; Heart failure; Trials; Type 2 diabetes mellitus.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Kannel W, McGee D (1979) Diabetes and cardiovascular risk factors: the Framingham study. Circulation. 59:8–13 - PubMed - DOI
    1. Ofstad AP, Atar D, Gullestad L, Langslet G, Johansen OE (2018) The heart failure burden of type 2 diabetes mellitus—a review of pathophysiology and interventions. Heart Fail Rev 23:303–323 - PubMed - PMC - DOI
    1. Ingle L, Reddy P, Clark AL, Cleland JG (2006) Diabetes lowers six-minute walk test performance in heart failure. J Am Coll Cardiol 47:1909–1910 - PubMed - DOI
    1. Egstrup M, Kistorp CN, Schou M, Høfsten DE, Møller JE, Tuxen CD, Gustafsson I (2013) Abnormal glucose metabolism is associated with reduced left ventricular contractile reserve and exercise intolerance in patients with chronic heart failure. Eur Heart J Cardiovasc Imaging 14:349–357 - PubMed - DOI
    1. Kristensen SL, Mogensen UM, Jhund PS, Petrie MC, Preiss D, Win S, Køber L, McKelvie R, Zile MR, Anand IS, Komajda M, Gottdiener JS, Carson PE, McMurray J (2017) Clinical and echocardiographic characteristics and cardiovascular outcomes according to diabetes status in patients with heart failure and preserved ejection fraction: a report from the I-Preserve trial (Irbesartan in Heart Failure With Preserved Ejection Fraction). Circulation. 135:724–735 - PubMed - DOI

MeSH terms

Substances

LinkOut - more resources