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. 2021 Apr 3;10(3):341-344.
doi: 10.1093/jpids/piaa047.

Rothia mucilaginosa Infections in Pediatric Cancer Patients

Rachel B Getzenberg  1 , Diego R Hijano  2 , Hana Hakim  2 , Ronald H Dallas  2 , Jose A Ferrolino  2 , Jessica Brazelton de Cardenas  3 , Cherilyn D Garner  3 , Li Tang  4 , Yin Su  4 , Joshua Wolf  2 , Randall T Hayden  3 , Gabriela Maron  2
Affiliations

Rothia mucilaginosa Infections in Pediatric Cancer Patients

Rachel B Getzenberg et al. J Pediatric Infect Dis Soc. .

Abstract

We performed a retrospective study to determine the epidemiology of Rothia mucilaginosa infections among pediatric cancer patients. Over 20 years, 37 cases were identified; 27% developed complications, but there was no infection-related mortality. All cases were successfully treated with vancomycin.

Keywords: Rothia mucilaginosa; bacteremia; cancer; children; infection.

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Figures

Figure 1.
Figure 1.
Flowchart of subject selection included in final analysis. aSeventy-one percent of patients had positive blood cultures only from a central venous catheter (CVC); 29% had positive blood cultures from both CVC and peripheral sites. bSusceptibility analysis was performed, but is not reported in 66 isolates due to poor growth in culture media. cPhysicians reviewed clinical signs and symptoms at the time of infection, number and time to positivity of blood cultures, and alternative diagnosis. Abbreviations: CVC, central venous catheter; TMP-SMX, trimethoprim-sulfamethoxazole.
See this image and copyright information in PMC

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Supplementary concepts