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Review
. 2020 Jul;36(2):487-496.
doi: 10.1016/j.cvfa.2020.03.007.

Bovine Respiratory Disease Treatment Failure: Impact and Potential Causes

Calvin W Booker  1 , Brian V Lubbers  2
Affiliations
Review

Bovine Respiratory Disease Treatment Failure: Impact and Potential Causes

Calvin W Booker et al. Vet Clin North Am Food Anim Pract. 2020 Jul.

Abstract

Bovine respiratory disease (BRD) is often attributed to complex interactions between the host, pathogen, and the environment. Likewise, many BRD treatment failures result from interactions between the host, pathogen, environment, drug, and drug administrator. Investigating and addressing the underlying causes of BRD treatment failures can improve clinical outcomes and animal welfare of future cases, improve morale of employees, reduce direct costs of dealing with BRD treatment failures, refine antimicrobial prescribing practices, and advance antimicrobial stewardship. This article discusses these interactions and provides guidance to veterinary practitioners on evaluating the success of treatment protocols.

Keywords: Antimicrobial; Bovine respiratory disease; Treatment failure.

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Conflict of interest statement

Disclosure C.W. Booker has received consulting and/or speaking honoraria from Bayer Animal Health, Boehringer Ingelheim Animal Health, Elanco Animal Health, Merck Animal Health, Phibro Animal Health, Vetoquinol, and Zoetis. B.V. Lubbers has received consulting and/or speaking honoraria from Merck Animal Health, Boehringer Ingelheim Vetmedica, Bayer Animal Health, and Zoetis.

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