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Review
. 2021 Jun;35(6):1860-1865.
doi: 10.1053/j.jvca.2020.04.041. Epub 2020 Apr 30.

Coronavirus Disease-2019 (COVID-19) and Cardiovascular Complications

Lulu Ma  1 , Kaicheng Song  1 , Yuguang Huang  2
Affiliations
Review

Coronavirus Disease-2019 (COVID-19) and Cardiovascular Complications

Lulu Ma et al. J Cardiothorac Vasc Anesth. 2021 Jun.

Abstract

The coronavirus disease-2019 (COVID-19) has become a global pandemic. It has spread to more than 100 countries, and more than 1 million cases have been confirmed. Although coronavirus causes severe respiratory infections in humans, accumulating data have demonstrated cardiac complications and poor outcome in patients with COVID-19. A large percent of patients have underlying cardiovascular disease, and they are at a high risk of developing cardiac complications. The basics of the virus, the clinical manifestations, and the possible mechanisms of cardiac complications in patients with COVID-19 are reviewed. Before an effective vaccine or medicine is available, supportive therapy and identifying patients who are at high risk of cardiac complications are important.

Keywords: cardiac complications; cardiac injury; coronavirus disease-2019; inflammatory factors; pneumonia.

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Conflict of interest statement

None.

Figures

Fig 1
Fig 1
Possible mechanisms of cardiac complications in patients with coronavirus disease-2019. V/Q, ventilation/perfusion.
See this image and copyright information in PMC

References

    1. Johns Hopkins University and Medicine. COVID-19 dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins. Available at: https://coronavirus.jhu.edu/map.html. Accessed April 15.
    1. Guo T., Fan Y., Chen M., et al. Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) JAMA Cardiol. 2020 Mar 27 [E-pub ahead of print] - PMC - PubMed
    1. Wu Z., McGoogan J.M. Characteristics of and important lessons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020 Feb 24 [E-pub ahead of print] - PubMed
    1. Zhu N., Zhang D., Wang W., et al. A novel coronavirus from patients with pneumonia in China, 2019. N Engl J Med. 2020;382:727–733. - PMC - PubMed
    1. Lu R., Zhao X., Li J., et al. Genomic characterisation and epidemiology of 2019 novel coronavirus: Implications for virus origins and receptor binding. Lancet. 2020;395:565–574. - PMC - PubMed