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. 2020 Oct 15;75(11):2231-2232.
doi: 10.1093/gerona/glaa131.

APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort

Chia-Ling Kuo  1   2 , Luke C Pilling  2   3 , Janice L Atkins  3 , Jane A H Masoli  3   4 , João Delgado  3 , George A Kuchel  2 , David Melzer  2   3
Affiliations

APOE e4 Genotype Predicts Severe COVID-19 in the UK Biobank Community Cohort

Chia-Ling Kuo et al. J Gerontol A Biol Sci Med Sci. .
No abstract available

Keywords: APOE; COVID-19; Genetic.

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References

    1. Atkins JL, Masoli JAH, Delgado J, Pilling LC, Kuo C-LC, Kuchel G, Melzer D. Preexisting comorbidities predicting severe COVID-19 in older adults in the UK biobank community cohort. medRxiv [Internet]. 2020. http://medrxiv.org/content/early/2020/05/08/2020.05.06.20092700.abstract. Accessed May 4, 2020.
    1. Docherty AB, Harrison EM, Green CA, et al. Features of 16,749 hospitalised UK patients with COVID-19 using the ISARIC WHO clinical characterisation protocol. medRxiv [Internet]. 2020. http://medrxiv.org/content/early/2020/04/28/2020.04.23.20076042.abstract. Accessed May 6, 2020.
    1. Mao L, Wang M, Chen S, et al. Neurological manifestations of hospitalized patients with COVID-19 in Wuhan, China: a retrospective case series study. JAMA Neurol. 2020. doi:10.1001/jamaneurol.2020.1127 - DOI - PMC - PubMed
    1. Kuo C-L, Pilling LC, Atkins JL, Kuchel GA, Melzer D. ApoE e2 and aging-related outcomes in 379,000 UK Biobank participants. medRxiv [Internet]. 2020. http://medrxiv.org/content/early/2020/02/13/2020.02.12.20022459.abstract. Accessed May 4, 2020. - PMC - PubMed
    1. Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-analysis. Journal of the American Medical Association. 1997;278:1349–1356. doi:10.1001/jama.1997.03550160069041z - DOI - PubMed

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