Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2022 Jan 1;18(1):e140-e155.
doi: 10.1097/PTS.0000000000000720.

Failure to Rescue Deteriorating Patients: A Systematic Review of Root Causes and Improvement Strategies

Affiliations

Failure to Rescue Deteriorating Patients: A Systematic Review of Root Causes and Improvement Strategies

Joshua R Burke et al. J Patient Saf. .

Abstract

Objectives: "Failure to rescue" (FTR) is the failure to prevent a death resulting from a complication of medical care or from a complication of underlying illness or surgery. There is a growing body of evidence that identifies causes and interventions that may improve institutional FTR rates. Why do patients "fail to rescue" after complications in hospital? What clinically relevant interventions have been shown to improve organizational fail to rescue rates? Can successful rescue methods be classified into a simple strategy?

Methods: A systematic review was performed and the following electronic databases searched between January 1, 2006, to February 12, 2018: MEDLINE, PsycINFO, Cochrane Library, CINAHL, and BNI databases. All studies that explored an intervention to improve failure to rescue in the adult population were considered.

Results: The search returned 1486 articles. Eight hundred forty-two abstracts were reviewed leaving 52 articles for full assessment. Articles were classified into 3 strategic arms (recognize, relay, and react) incorporating 6 areas of intervention with specific recommendations.

Conclusions: Complications occur consistently within healthcare organizations. They represent a huge burden on patients, clinicians, and healthcare systems. Organizations vary in their ability to manage such events. Failure to rescue is a measure of institutional competence in this context. We propose "The 3 Rs of Failure to Rescue" of recognize, relay, and react and hope that this serves as a valuable framework for understanding the phases where failure of patient salvage may occur. Future efforts at mitigating the differences in outcome from complication management between units may benefit from incorporating this proposed framework into institutional quality improvement.

PubMed Disclaimer

Conflict of interest statement

The authors disclose no conflict of interest.

Similar articles

Cited by

References

    1. Silber JH, Williams SV, Krakauer H, et al. Hospital and patient characteristics associated with death after surgery. A study of adverse occurrence and failure to rescue. Med Care . 1992;30:615–629.
    1. Mant J. Process versus outcome indicators in the assessment of quality of health care. Int J Qual Health Care . 2001;13:475–480.
    1. National Patient Safety Agency. Recognising and responding appropriately to early signs of deterioration in hospitalised patients. Available at: https://www.patientsafetyoxford.org/wp-content/uploads/2018/03/NPSA-Dete... . Accessed April 24, 2020.
    1. Linda TK, Janet MC, Molla SD. Agency for Healthcare Research and Quality. Patient Safety Indicators (PSI) Version 3.1 Comparative Data Agency for Healthcare Research and Quality. Available at: https://www.qualityindicators.ahrq.gov/Downloads/Modules/PSI/V31/psi_gui... . Accessed April 24, 2020.
    1. Institute of Medicine. To Err Is Human: Building a safer Health System. Kohn, LT, Corrigan JA, Donaldson MS (eds). Institute of Medicine (US) Committee on Quality of Health Care in America. Washington, DC: National Academies Press (US); 2000.

Publication types

LinkOut - more resources