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. 2020 Jun:56:102473.
doi: 10.1016/j.ebiom.2019.09.053. Epub 2020 May 23.

First evidence that senolytics are effective at decreasing senescent cells in humans

Georgina M Ellison-Hughes  1
Affiliations

First evidence that senolytics are effective at decreasing senescent cells in humans

Georgina M Ellison-Hughes. EBioMedicine. 2020 Jun.
No abstract available

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Conflict of interest statement

Declaration of Competing Interest The author declares no conflicts of interest.

References

    1. Herbig U., Ferreira M., Condel L., Carey D., Sedivy J.M. Cellular senescence in aging primates. Science. 2006;311(5765):1257. doi: 10.1126/science.1122446. - DOI - PubMed
    1. Xu M., Pirtskhalava T., Farr J.N., Weigand B.M., Palmer A.K., Weivoda M.M. Senolytics improve physical function and increase lifespan in old age. Nat Med. 2018;24:1246–1256. doi: 10.1038/s41591-018-0092-9. - DOI - PMC - PubMed
    1. Kirkland J.L., Tchkonia T., Zhu Y., Niedernhofer L.J., Robbins P.D. The clinical potential of senolytic drugs. J Am Geriatr Soc. 2017;65:2297–2301. doi: 10.1111/jgs.14969. - DOI - PMC - PubMed
    1. Kirkland J.L., Tchkonia T. Cellular senescence: a translational perspective. EBioMedicine. 2017;21:21–28. doi: 10.1016/j.ebiom.2017.04.013. - DOI - PMC - PubMed
    1. Tchkonia T., Kirkland J.L. Aging, cell senescence, and chronic disease: emerging therapeutic strategies. JAMA. 2018;320:1319–1320. doi: 10.1001/jama.2018.12440. - DOI - PubMed