COVID-19 and Nasal Cytobrush Cytology

doi:10.1159/000508768

. 2020;64(4):397-398.

doi: 10.1159/000508768. Epub 2020 May 26.

COVID-19 and Nasal Cytobrush Cytology

Matteo Gelardi¹, Mario Notargiacomo², Eleonora M C Trecca³, Michele Cassano¹, Giorgio Ciprandi⁴

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia, Italy.
² Department of Otolaryngology-Head and Neck Surgery, Melzo Hospital, Milan, Italy.
³ Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia, Italy, eleonora.trecca@unifg.it.
⁴ Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

PMID: 32454497
PMCID: PMC7316649
DOI: 10.1159/000508768

COVID-19 and Nasal Cytobrush Cytology

Matteo Gelardi et al. Acta Cytol. 2020.

. 2020;64(4):397-398.

doi: 10.1159/000508768. Epub 2020 May 26.

Authors

Matteo Gelardi¹, Mario Notargiacomo², Eleonora M C Trecca³, Michele Cassano¹, Giorgio Ciprandi⁴

Affiliations

¹ Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia, Italy.
² Department of Otolaryngology-Head and Neck Surgery, Melzo Hospital, Milan, Italy.
³ Department of Otolaryngology-Head and Neck Surgery, University Hospital of Foggia, Foggia, Italy, eleonora.trecca@unifg.it.
⁴ Allergy Clinic, Casa di Cura Villa Montallegro, Genoa, Italy.

PMID: 32454497
PMCID: PMC7316649
DOI: 10.1159/000508768

No abstract available

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Conflict of interest statement

The authors have no conflicts of interest to declare.

Figures

**Fig. 1**
a Nasal cytology within normal limits (May-Grünwald-Giemsa, ×800× magnification). b Normal ciliated cell. The arrow indicates the “hyperchromatic supranuclear stria” (SNS; May-Grünwald-Giemsa, ×2,000 magnification). c Nasal cytology in a COVID-19 patient (May-Grünwald-Giemsa, ×400 magnification). d Nasal cytology in a COVID-19 patient evidencing absence of the hyperchromatic SNS (May-Grünwald-Giemsa, ×1,000 magnification). Ci, ciliated cell; N, neutrophils.

See this image and copyright information in PMC

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References

1. Xydakis MS, Dehgani-Mobaraki P, Holbrook EH, Geisthoff UW, Bauer C, Hautefort C, et al. Smell and taste dysfunction in patients with COVID-19. Lancet Infect Dis. 2020 Apr;S1473-3099((20)):30293–0. - PMC - PubMed
1. Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, et al. HCA Lung Biological Network SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 2020 May;26((5)):681–7. - PMC - PubMed
1. Doyle WJ, Gentile DA, Skoner DP. Viral and bacterial rhinitis. Clin Allergy Immunol. 2007;19:177–95. - PubMed
1. Gelardi M, Ciprandi G. Ciliocytophthoria of nasal epithelial cells after viral infection: a sign of suffering cell. Acta Biomed. 2019 Jan;90(2-S):7–9. - PMC - PubMed
1. Aslani FS, Khademi B, Yeganeh F, Kumar PV, Bedayat GR. Nasal cytobrush cytology: evaluation of the hyperchromatic supranuclear stria. Acta Cytol. 2006 Jul-Aug;50((4)):430–4. - PubMed

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[1] Xydakis MS, Dehgani-Mobaraki P, Holbrook EH, Geisthoff UW, Bauer C, Hautefort C, et al. Smell and taste dysfunction in patients with COVID-19. Lancet Infect Dis. 2020 Apr;S1473-3099((20)):30293–0. - PMC - PubMed

[2] Xydakis MS, Dehgani-Mobaraki P, Holbrook EH, Geisthoff UW, Bauer C, Hautefort C, et al. Smell and taste dysfunction in patients with COVID-19. Lancet Infect Dis. 2020 Apr;S1473-3099((20)):30293–0. - PMC - PubMed

[3] Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, et al. HCA Lung Biological Network SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 2020 May;26((5)):681–7. - PMC - PubMed

[4] Sungnak W, Huang N, Bécavin C, Berg M, Queen R, Litvinukova M, et al. HCA Lung Biological Network SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 2020 May;26((5)):681–7. - PMC - PubMed

[5] Doyle WJ, Gentile DA, Skoner DP. Viral and bacterial rhinitis. Clin Allergy Immunol. 2007;19:177–95. - PubMed

[6] Doyle WJ, Gentile DA, Skoner DP. Viral and bacterial rhinitis. Clin Allergy Immunol. 2007;19:177–95. - PubMed

[7] Gelardi M, Ciprandi G. Ciliocytophthoria of nasal epithelial cells after viral infection: a sign of suffering cell. Acta Biomed. 2019 Jan;90(2-S):7–9. - PMC - PubMed

[8] Gelardi M, Ciprandi G. Ciliocytophthoria of nasal epithelial cells after viral infection: a sign of suffering cell. Acta Biomed. 2019 Jan;90(2-S):7–9. - PMC - PubMed

[9] Aslani FS, Khademi B, Yeganeh F, Kumar PV, Bedayat GR. Nasal cytobrush cytology: evaluation of the hyperchromatic supranuclear stria. Acta Cytol. 2006 Jul-Aug;50((4)):430–4. - PubMed

[10] Aslani FS, Khademi B, Yeganeh F, Kumar PV, Bedayat GR. Nasal cytobrush cytology: evaluation of the hyperchromatic supranuclear stria. Acta Cytol. 2006 Jul-Aug;50((4)):430–4. - PubMed

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COVID-19 and Nasal Cytobrush Cytology

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COVID-19 and Nasal Cytobrush Cytology

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