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Case Reports
. 2020 May 11:2020:4056901.
doi: 10.1155/2020/4056901. eCollection 2020.

Metastasis of Papillary Thyroid Carcinoma to the Maxillary Sinus: Case Report and Review of the Literature

Hajime Shimmura  1 , Eri Mori  1 , Rumi Sekine  1 , Masayoshi Tei  1 , Nobuyoshi Otori  1
Affiliations
Case Reports

Metastasis of Papillary Thyroid Carcinoma to the Maxillary Sinus: Case Report and Review of the Literature

Hajime Shimmura et al. Case Rep Otolaryngol. .

Abstract

Metastasis of the thyroid carcinoma to the paranasal sinuses is rarely reported. Among these sinuses, metastasis to the maxillary sinus alone has been reported only in a few cases. This is the first reported case in a 76-year-old woman with papillary thyroid carcinoma metastasizing to the maxillary sinus alone and resected through endoscopic sinonasal surgery. When patients have sinus lesions and a history of malignancy, metastasis should be included in the differential diagnosis. If they have an isolated metastatic lesion to the paranasal sinus, ESS, either palliative or radical, can be a useful treatment option.

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Conflict of interest statement

The authors declare that they have no conflicts of interest.

Figures

Figure 1
Figure 1
Initial images. CT: shadow of the soft-tissue density of the right maxillary sinus; T2W: well-circumscribed, smoothly marginated tumor with a peripheral low area and a central inhomogeneous area.
Figure 2
Figure 2
(a) Right maxillary sinus opened with endoscopic modified medial maxillectomy. (b) Tumor (3 × 2 cm) in the right maxillary sinus (with a 70° endoscope). (c) Bleeding from the feeding artery based on the anterior wall of the right maxillary sinus. (d) Feeding artery cauterized and unblocked tumor resected.
Figure 3
Figure 3
Post-ESS images. CT: Resected tumor in the right maxillary sinus.
Figure 4
Figure 4
(a) Papillary structure. Cell nuclei are slightly larger with coarsely granular chromatin (hematoxylin and eosin, 100×). (b, c) Immunohistochemical staining revealed tumor cells positive for thyroid transcription factor 1 (TTF-1) (positive for carcinoma arising from follicular epithelial cells) and thyroglobulin.
See this image and copyright information in PMC

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