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Case Reports
. 2020 Mar 30;5(2):96-100.
doi: 10.7150/jbji.43801. eCollection 2020.

Clostridium cadaveris Osteomyelitis: an Unusual Pathogen which Highlights the Importance of Deep Tissue Sampling in Chronic Osteomyelitis

Ruth Alexandra Corrigan  1   2 , Jose Lomas-Cabeza  1 , David Stubbs  1 , Martin McNally  1
Affiliations
Case Reports

Clostridium cadaveris Osteomyelitis: an Unusual Pathogen which Highlights the Importance of Deep Tissue Sampling in Chronic Osteomyelitis

Ruth Alexandra Corrigan et al. J Bone Jt Infect. .

Abstract

Clostridium cadaveris, named following its identification in human corpses, is an unusual pathogen. We report the first case of C. cadaveris osteomyelitis. This case highlights the importance of deep tissue sampling and appropriate culture to correctly identify causative pathogens and guide targeted antimicrobial therapy in difficult-to-treat infections like chronic osteomyelitis.

Keywords: Chronic osteomyelitis; Clostridium cadaveris; intra-operative sampling.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interest exists.

Figures

Figure 1
Figure 1
Pre-operative radiograph (a) and MRI (b) suggestive of Cierny and Mader Stage 3 osteomyelitis of the lower tibia.
Figure 1
Figure 1
Pre-operative radiograph (a) and MRI (b) suggestive of Cierny and Mader Stage 3 osteomyelitis of the lower tibia.
Figure 2
Figure 2
Post-operative radiographs with gentamicin eluting, bioabsorbable composites visible at the site of osteomyelitis excision.
Figure 3
Figure 3
Radiograph (a) at 10 months showing a small radiodense area of extruded antibiotic carrier adjacent to the tibialis posterior tendon. The bone defect has remodelled well with no sign of recurrent infection. At operation, a 1x2x2.5cm soft mass of calcium sulphate was removed (b).
See this image and copyright information in PMC

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