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. 2020 May 1;21(5):1487-1494.
doi: 10.31557/APJCP.2020.21.5.1487.

GLOBAL Leukemia in Children 0-14 Statistics 2018, Incidence and Mortality and Human Development Index (HDI): GLOBOCAN Sources and Methods

Seyedeh Mahdieh Namayandeh  1 , Zaher Khazaei  2 , Moslem Lari Najafi  3 , Elham Goodarzi  4 , Alireza Moslem  5
Affiliations

GLOBAL Leukemia in Children 0-14 Statistics 2018, Incidence and Mortality and Human Development Index (HDI): GLOBOCAN Sources and Methods

Seyedeh Mahdieh Namayandeh et al. Asian Pac J Cancer Prev. .

Abstract

Objective: Cancer is the second leading cause of death in children under 15 and leukemia is the most common type of cancer in this age group. The aim of the present study is to investigate the incidence and mortality of leukemia in children aged 0-14 years and its relationship with Human Development Index (HDI in different countries of the world. Methods: Incidence and mortality rates were obtained from GLOBOCAN and Country's income from World Bank. The data analysis was conducted using correlation analysis. The association of incidence and mortality rates with HDI was investigated using linear regression models.

Results: The results revealed a significant positive correlation between the incidence rate and Gross National Income per capita (r = 0.464, P <0.0001), mean years of schooling (r = 0.566, P <0.0001), life expectancy at birth (r = 0.712, P <0.0001) and expected years of schooling (r = 0.604, P <0.0001). The results also demonstrated a positive and significant correlation between mortality rate and life expectancy at birth (r = 0.199, P <0.0001). An improvement in HDI [Beta = 7.7, CI95% (0.1, 15.3)] and life Expectancy at birth [Beta = 0.1, CI95% (0.03, 0.1)] caused a significantly rise in the incidence of leukemia. Moreover, the improved HDI [Beta = 6.2, CI95% (1.9, 10.5)] was associated with increased mean years of schooling [Beta = -0.1, CI95% (-0.2, -0.01)] and expected years of schooling [Beta = -0.1, CI95% (-0.3, -0.08).

Conclusion: As the HDI increases, incidence and mortality from of leukemia increases indicating a change in factors that affects leukemia incidences.

Keywords: GLOBAL Incidence; Human Development Index; Leukemia; children; mortality.

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Figures

Figure 1
Figure 1
Pie Charts Present the Distribution of Cases and Mortality for the 7 Most Common Types of Cancers in 2018 for Both Sexes. For each sex, the area of pie chart shows the proportion of the total number of cases or deaths.[ Source: GLOBOCAN 2018].
Figure 2
Figure 2
Pie Charts Present the Distribution of Cases and Mortality by Continents in 2018 for Both Sexes. For each sex, the area of the pie chart shows the proportion of the total number of cases or deaths.[ Source: GLOBOCAN 2018].
Figure 3
Figure 3
Global Map Showing Age-Standardized. (A) incidence (B) mortality rates of leukemia in children aged 0-14 years in 2018. [Source: GLOBOCAN 2018]
Figure 4
Figure 4
Bar Charts Showing Age-Standardized Incidence and Mortality Rates of Leukemia Cancer for Children Aged 0-14 in Terms of by Human Development Index in 2018.[Source: GLOBOCAN 2018].
Figure 5
Figure 5
Correlation between the Incidence and Mortality Rates of Leukemia and HDI in (a) both sexes, (b) male and (c) females children aged 0-14 worldwide
See this image and copyright information in PMC

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