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Case Reports
. 2020 Jun;68(6):981-983.
doi: 10.4103/ijo.IJO_1308_20.

Sanitizer aerosol-driven ocular surface disease (SADOSD)-A COVID-19 repercussion?

Rohit Shetty  1 , Chaitra Jayadev  1 , Aishwarya Chabra  1 , Sonia Maheshwari  1 , Sharon D'Souza  1 , Pooja Khamar  1 , Swaminathan Sethu  1 , Santosh G Honavar  1
Affiliations
Case Reports

Sanitizer aerosol-driven ocular surface disease (SADOSD)-A COVID-19 repercussion?

Rohit Shetty et al. Indian J Ophthalmol. 2020 Jun.

Abstract

Since the onset of the COVID-19 pandemic, there has been an advisory for regular and thorough cleaning of hands besides other measures such as social distancing and self-isolation. The rationale for the same is to prevent the transfer of the virus from hands that have come in contact with fomites. While both alcohol-based hand rubs (ABHR) or washing with soap and water are claimed to have been effective, hand sanitizers have gained more popularity due to the ease of use. The increased frequency of ABHR use and the aerosols generated pose a potential threat to the skin and exposed mucosal surfaces, especially that of the eye due to the proximity of use. The adverse effects of alcohol in these sanitizers can be manifold. An allergic or inflammatory response can occur depending on the predisposing or preexisting conditions. This article describes the risks, underlying mechanisms, and preventive measures for sanitizer aerosol-driven ocular surface disease.

Keywords: Alcohol-based hand rubs; COVID; sanitizer aerosol-driven ocular surface disease.

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Conflict of interest statement

None

Figures

Figure 1
Figure 1
Precautionary measures to prevent sanitizer aerosol-driven ocular surface disease
See this image and copyright information in PMC

References

    1. Boyce JM. Using alcohol for hand antisepsis: Dispelling old myths. Infect Control Hosp Epidemiol. 2000;21:438–41. - PubMed
    1. Boyce JM, Pittet D Healthcare Infection Control Practices Advisory Committee; HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force. Guideline for Hand Hygiene in Health-Care Settings Recommendations of the Healthcare Infection Control Practices Advisory Committee and the HICPAC/SHEA/APIC/IDSA Hand Hygiene Task Force Society for Healthcare Epidemiology of America/Association for Professionals in Infection Control/Infectious Diseases Society of America MMWR PMID: 12418624 - PubMed
    1. Maier A, Ovesen JL, Allen CL, York RG, Gadagbui BK, Kirman CR, et al. Safety assessment for ethanol-based topical antiseptic use by health care workers: Evaluation of developmental toxicity potential. Regul Toxicol Pharmacol. 2015;73:248–64. - PubMed
    1. Bessonneau V, Thomas O. Assessment of exposure to alcohol vapor from alcohol-based hand rubs. Int J Environ Res Public Health. 2012;9:868–79. - PMC - PubMed
    1. Abo T, Yuki T, Xu R, Araki D, Takahashi Y, Sakaguchi H, et al. Expansion of the applicability domain for highly volatile substances on the short time exposure test method and the predictive performance in assessing eye irritation potential. J Toxicol Sci. 2018;43:407–22. - PubMed

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