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. 2021 Feb;278(2):323-329.
doi: 10.1007/s00405-020-06075-8. Epub 2020 May 28.

Cochlear implantation in prelingually deaf children with white matter lesions

Shanwen Chen  1 , Wenwen Zheng  2 , Hanli Li  3 , Mei Zhong  1 , Rui Wei  1 , Biaoxin Zhang  1 , Busheng Tong  1 , Jianxin Qiu  4   5 , Kun Yao  6
Affiliations

Cochlear implantation in prelingually deaf children with white matter lesions

Shanwen Chen et al. Eur Arch Otorhinolaryngol. 2021 Feb.

Abstract

Objective: White matter lesions (WMLs) are the most common central nervous system changes observed during cochlear implant evaluation. However, its clinical significance in cochlear implantation (CI) remains unclear. The purpose of this study is to explore the effects of WMLs on hearing and speech rehabilitation of prelingually deaf children after CI.

Methods: The data of forty-five children with WMLs who received CI from 2011 to 2014 were retrospectively reviewed. All patients underwent magnetic resonance imaging examination preoperatively. The categories of auditory performance (CAP) and speech intelligibility rating (SIR) scales were used to evaluate changes in the auditory and speech abilities of the patients, and the Fazekas scale was adopted to assess the extent of WMLs. The degree of WMLs was divided into four grades (none, mild, moderate, severe). We assessed hearing and speech abilities at the following time points: 6, 12, 24, 36, 48 and 60-months post-operation.

Results: No significant differences in CAP scores were observed between WMLs groups and the control group at 12 months post-CI (p = 0.099), but marked between-group differences were found at 6, 24, 48- and 60-months post-CI. (p < 0.05). Similarly, no significant differences in the SIR scores were observed at 6 months post-CI (p = 0.087), but marked between-group differences were found at 12, 24, 48- and 60- months post-CI. (p < 0.05). Analysis of stratified group results revealed improvements in hearing and speech development for all the subgroups, including the severe WMLs subgroup following CI. However, hearing and speech ability of the severe WMLs subgroup was much slower than that of other groups.

Conclusions: The auditory and speech abilities of prelingually deaf children with WMLs and those without WMLs can improve after CI. Therefore, WMLs should not be considered a contraindication for CI. However, the decision to perform CI in such patients needs a comprehensive evaluation because the post-surgery effects on children with severe WMLs are not ideal.

Keywords: Children; Cochlear implantation; Sensorineural hearing loss; Speech rehabilitation; White matter lesions.

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References

    1. Wilson BS, Tucci DL, Merson MH, O'Donoghue GM (2017) Global hearing health care: new findings and perspectives. The Lancet 390(10111):2503–2515. https://doi.org/10.1016/S0140-6736(17)31073-5 - DOI
    1. Hong P, Jurkowski ZC, Carvalho DS (2010) Preoperative cerebral magnetic resonance imaging and white matter changes in pediatric cochlear implant recipients. Int J Pediatr Otorhinolaryngol 74(6):658–660. https://doi.org/10.1016/j.ijporl.2010.03.014 - DOI - PubMed
    1. Jonas NE, Ahmed J, Grainger J, Jephson CG, Wyatt ME, Hartley BE, Saunders D, Cochrane LA (2012) MRI brain abnormalities in cochlear implant candidates: How common and how important are they? Int J Pediatr Otorhinolaryngol 76(7):927–929. https://doi.org/10.1016/j.ijporl.2012.02.070 - DOI - PubMed
    1. Lapointe A, Viamonte C, Morriss MC, Manolidis S (2006) Central nervous system findings by magnetic resonance in children with profound sensorineural hearing loss. Int J Pediatr Otorhinolaryngol 70(5):863–868. https://doi.org/10.1016/j.ijporl.2005.09.022 - DOI - PubMed
    1. Young JY, Ryan ME, Young NM (2014) Preoperative imaging of sensorineural hearing loss in pediatric candidates for cochlear implantation. Radiographics Rev Publ Radiol Soc N Am Inc 34(5):133–149. https://doi.org/10.1148/rg.345130083 - DOI

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